Trimethylamine oxide supplementation differentially regulates fat deposition in liver, longissimus dorsi muscle and adipose tissue of growing-finishing pigs

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成果类型：

期刊论文

作者：

Zha, Andong;Li, Wanquan;Wang, Jing;Bai, Ping;Qi, Ming;...

通讯作者：

Tan, B

作者机构：

[Zha, Andong; Qi, Ming; Yin, Yulong; Liao, Peng] Chinese Acad Sci, Inst Subtrop Agr, Lab Anim Nutr Physiol & Metab Proc, Key Lab Agroecol Proc Subtrop Reg,Natl Engn Lab Po, Changsha 410125, Peoples R China.

[Li, Wanquan; Tan, Bie; Tan, B; Yin, Yulong; Wang, Jing] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Peoples R China.

[Zha, Andong; Qi, Ming; Yin, Yulong] Univ Chinese Acad Sci, Beijing 100008, Peoples R China.

[Bai, Ping; Yin, Yulong] Yunnan Southwest Agr & Anim Husb Grp Co Ltd, Kunming 650224, Peoples R China.

通讯机构：

[Tan, B ] H

Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Peoples R China.

语种：

英文

关键词：

Growing-finishing pig;Trimethylamine oxide;Fat deposition;Fatty acid composition;Intestinal microbiota

期刊：

动物营养(英文)

ISSN：

2405-6545

年：

2024

卷：

页码：

25-35

DOI：

10.1016/j.aninu.2023.12.006

基金类别：

National Natural Science Foundation of China [U20A2054]; Earmarked fund for China Agriculture Research System [CARS -35]; Science and Technology Major Project of Yunnan Province [202202AE090032]; Large-scale Healthy Breeding Technology Research and Industrialization Demonstration of pig [202102AE090046]

机构署名：

本校为通讯机构

院系归属：

动物科学技术学院

摘要：

Trimethylamine oxide (TMAO) is a microbiota-derived metabolite, and numerous studies have shown that it could regulate fat metabolism in humans and mice. However, few studies have focused on the effects of TMAO on fat deposition in growing-finishing pigs. This study aimed to investigate the effect of TMAO on fat deposition and intestinal microbiota in growing-finishing pigs. Sixteen growing pigs were randomly divided into 2 groups and fed with a basal diet with 0 or 1 g/kg TMAO for 149 d. The intestinal microbial profiles, fat deposition indexes, and fatty acid profiles were measured. These re...

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Trimethylamine oxide supplementation differentially regulates fat deposition in liver, longissimus dorsi muscle and adipose tissue of growing-finishing pigs

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