Lactobacillus plantarum alleviates high-fat diet-induced obesity by altering the structure of mice intestinal microbial communities and serum metabolic profiles

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成果类型：

期刊论文

作者：

Zhu, Junwen;Liu, Xueying;Liu, Naiyuan;Zhao, Ruochi;Wang, Shuangshuang

通讯作者：

Wang, SS

作者机构：

[Zhu, Junwen; Wang, Shuangshuang] Wenzhou Med Univ, Peoples Hosp Wenling 1, Wenling Hosp, Dept Cardiol, Wenling, Peoples R China.

[Zhu, Junwen; Liu, Xueying; Liu, Naiyuan] Hunan Agr Univ, Coll Biosci & Biotechnol, Hunan Prov Engn Res Ctr Appl Microbial Resources D, Changsha, Peoples R China.

[Zhao, Ruochi; Wang, Shuangshuang] Ningbo Univ, Affiliated Hosp 1, Key Lab Precis Med Atherosclerot Dis Zhejiang Prov, Ningbo, Peoples R China.

通讯机构：

[Wang, SS ] W

Wenzhou Med Univ, Peoples Hosp Wenling 1, Wenling Hosp, Dept Cardiol, Wenling, Peoples R China.

Ningbo Univ, Affiliated Hosp 1, Key Lab Precis Med Atherosclerot Dis Zhejiang Prov, Ningbo, Peoples R China.

语种：

英文

关键词：

Lactobacillus plantarum;differential metabolites;fat metabolism;intestinal microbes;obesity;probiotics

期刊：

Frontiers in Microbiology

ISSN：

1664-302X

年：

2024

卷：

页码：

1425764

DOI：

10.3389/fmicb.2024.1425764

基金类别：

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. The research was supported by the grants from: Zhejiang Provincial Program for Medicine and Health (2023KY411), Key Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province (Grant No. 2022E10026), Social Development Science and Technology Foundation of Taizhou (21ywb115), Social Development Science and Technology Foundation of Wenling (2021S00197) and Hunan Provincial Science and Technology Department (2019TP2004).

机构署名：

本校为其他机构

院系归属：

生物科学技术学院

摘要：

Obesity, which is always accompanied by disorders of lipid metabolism and dysbiosis of the gut microbiota, has become a global epidemic recognised by the World Health Organisation, necessitating innovative strategies and a globally accepted agreement on treating obesity and its related complications. Probiotics, as major active ingredients in many foods, offer potential as biological treatments for obesity prevention and management. Lactobacillus plantarum (L. plantarum) possesses a wide range of biological activities and is widely used to alleviate and ameliorate various diseases. This resear...

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Lactobacillus plantarum alleviates high-fat diet-induced obesity by altering the structure of mice intestinal microbial communities and serum metabolic profiles

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