Lactiplantibacillus plantarum and faecal microbiota transplantation can improve colitis in mice by affecting gut microbiota and metabolomics

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Yin, S.;Liao, Y.;Ma, Y.;Han, X.;Yang, Z.;...

通讯作者：

Fang, J

作者机构：

[Liao, Y.; Ma, Y.; Fang, J.; Yang, Z.; Han, X.; Yin, S.; Liu, G.; Fang, J] Hunan Agr Univ, Coll Biosci & Biotechnol, Hunan Prov Engn Res Ctr Appl Microbial Resources, Changsha 410128, Hunan, Peoples R China.

[Alahmadi, R. M.; Hatamleh, A. A.] King Saud Univ, Dept Bot & Microbiol, Coll Sci, POB 2455, Riyadh 11451, Saudi Arabia.

[Duraipandiyan, V.] Loyola Coll, Entomol Res Inst, Div Microbiol, Chennai 600034, Tamil Nadu, India.

[Gurusunathan, V. R.] Loyola Coll, Dept Plant Biol & Biotechnol, Chennai 600034, Tamil Nadu, India.

[Arokiyaraj, S.] Sejong Univ, Dept Food Sci & Biotechnol, Seoul 05006, South Korea.

通讯机构：

[Fang, J ] H

Hunan Agr Univ, Coll Biosci & Biotechnol, Hunan Prov Engn Res Ctr Appl Microbial Resources, Changsha 410128, Hunan, Peoples R China.

语种：

英文

关键词：

gut microbiota;Lactiplantibacillus plantarum;faecal microbiota transplantation;serum metabolites

期刊：

BENEFICIAL MICROBES

ISSN：

1876-2883

年：

2023

卷：

期：

页码：

609-622

DOI：

10.1163/18762891-20230046

基金类别：

National Natural Science Foundation of China [31772642, 31672457]; Ministry of Agricultural of the People's Republic of China [2015-Z64, 2016-X47]; Hunan Provincial Science and Technology Department [2021JJ30008, 2020NK2004, 2019TP2004, 2017NK2322, 2016WK2008, 2016TP2005]; Double first-class construction project of Hunan Agricultural University [SYL201802003]; Postgraduate Scientific Research Innovation Project of Hunan Province [CX20210654]; Science and Technology Innovation and Entrepreneurship Project for University Students of Hunan Province [2021RC1004]; King Saud University, Riyadh, Saudi Arabia [RSPD2023R543]

机构署名：

本校为第一且通讯机构

院系归属：

生物科学技术学院

摘要：

Gut microbiota may have therapeutic effects on inflammatory bowel disease (IBD). Regulating intestinal microbiota through Lactiplantibacillus plantarum (L. plantarum) and faecal microbiota transplantation (FMT) is a novel approach to treating IBD. This study aimed to explore the effect of L. plantarum and FMT pretreatment in alleviating colitis in mice. Five groups of mice (n = 6 per group) were included: CON group, DSS group (dextran sodium sulphate-induced colitis mice), LP-DSS pretreatment group (colitis mice were given strain L. plantarum and 5% DSS), DSS-FMT group (mice pretreated with fa...

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Lactiplantibacillus plantarum and faecal microbiota transplantation can improve colitis in mice by affecting gut microbiota and metabolomics

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