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Genome-Wide Association Study and Identification of Candidate Genes for Intramuscular Fat Fatty Acid Composition in Ningxiang Pigs

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成果类型:
期刊论文
作者:
Zeng, Qinghua;Gao, Hu;Yin, Shishu;Peng, Yinglin;Yang, Fang;...
通讯作者:
Yin, YL;Yin, Yulong;Xu, K
作者机构:
[Song, Gang; Gao, Hu; He, Jun; Jin, Zhao; Yin, Yulong; Zeng, Qinghua; Yin, Shishu; Fu, Yawei; Wang, Qian; Yang, Fang; Yin, YL] Hunan Agr Univ, Coll Anim Sci & Technol, Anim Nutr Genome & Germplasm Innovat Res Ctr, Changsha 410128, Peoples R China.
[Song, Gang; Gao, Hu; Xu, Kang; Jin, Zhao; Yin, Yulong; Chen, Yue; Fu, Yawei; Wang, Qian; Deng, Xiaoxiao; Hou, Xiaohong; Yin, YL] Chinese Acad Sci, Inst Subtrop Agr, Lab Anim Nutr Physiol & Metab, Changsha 410125, Peoples R China.
[Peng, Yinglin] Hunan Inst Anim & Vet Sci, Changsha 410131, Peoples R China.
[Xu, Kang; Yin, Yulong; Yin, YL] Guangdong Lab Lingnan Modern Agr, Guangzhou 510642, Peoples R China.
通讯机构:
[Xu, K ; Yin, YL] C
[Yin, YL ] H
Hunan Agr Univ, Coll Anim Sci & Technol, Anim Nutr Genome & Germplasm Innovat Res Ctr, Changsha 410128, Peoples R China.
Chinese Acad Sci, Inst Subtrop Agr, Lab Anim Nutr Physiol & Metab, Changsha 410125, Peoples R China.
Guangdong Lab Lingnan Modern Agr, Guangzhou 510642, Peoples R China.
语种:
英文
关键词:
longissimus dorsi;saturated fatty acids;monounsaturated fatty acids;polyunsaturated fatty acids;GWAS
期刊:
ANIMALS
ISSN:
2076-2615
年:
2023
卷:
13
期:
20
页码:
3192-
基金类别:
Conceptualization, Q.Z., H.G. and Y.Y.; methodology, H.G. and K.X.; software, Q.Z., G.S. and X.D.; validation, H.G. and S.Y.; formal analysis, Q.Z. and F.Y.; investigation, Y.P., Y.C. and X.H.; resources, J.H., Y.Y. and K.X.; data curation, F.Y., Y.F., Q.W., S.Y. and Z.J.; writing—original draft preparation, Q.Z., H.G., S.Y. and F.Y.; writing—review and editing, J.H., Y.P., Y.Y. and K.X. visualization, H.G. and S.Y.; supervision, Y.Y. and K.X.; project administration, Y.Y. and K.X.; funding acquisition, Y.Y. and K.X. All authors have read and agreed to the published version of the manuscript. This research was funded by the Laboratory of Lingnan Modern Agriculture Project (NT2021005), the Strategic Priority Research Program of Chinese Academy of Sciences (Grant No. XDA24030204), the Special Funds for the Construction of Innovative Provinces in Hunan (Grant numbers 2021NK1009 and 2021NK1012); the Natural Science Foundation of Hunan Province Project (2023JJ20043 and 2020JJ5635).
机构署名:
本校为第一且通讯机构
院系归属:
动物科学技术学院
摘要:
Simple Summary: In this study, we conducted a comprehensive investigation of the fatty acid composition in Ningxiang pigs using a genome-wide association study. Our findings revealed a combination of previously reported and novel candidate genes associated with saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs), and polyunsaturated fatty acids (PUFAs). Notably, we identified significant single-nucleotide polymorphisms (SNPs) that are closely linked to specific fatty acids, and some of these genes explained substantial phenotypic variance. These noteworthy discoveries have the po...

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