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Soybean oil induces neuroinflammatory response through brain-gut axis under high-fat diet

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成果类型:
期刊论文
作者:
Liu, Xiangyan;Tao, Ran;Guo, Fangrui;Zhang, Linyu;Qu, Jianyu;...
通讯作者:
Wen, Lixin;Wang, J
作者机构:
[Li, Mengyao; Wu, Xiaoran; Wang, Ji; Wen, Lixin; Tao, Ran; Zhu, Yuanyuan; Zhang, Linyu; Liu, Xiangyan; Guo, Fangrui; Qu, Jianyu; Wen, LX; Wang, J] Hunan Agr Univ, Coll Vet Med, Hunan Engn Res Ctr Livestock & Poultry Hlth Care, Changsha 410128, Peoples R China.
[Wang, Xianglin] Changsha Lvye Biotechnol Co Ltd, Changsha 410100, Peoples R China.
[Wang, Ji] Hunan Agr Univ, Coll Anim Sci & Technol, Anim Nutr Genome & Germplasm Innovat Res Ctr, Changsha 410128, Peoples R China.
通讯机构:
[Wen, LX; Wang, J ] H
Hunan Agr Univ, Coll Vet Med, Hunan Engn Res Ctr Livestock & Poultry Hlth Care, Changsha 410128, Peoples R China.
语种:
英文
关键词:
Dietary fat;Neuroinflammation;Gut microbiota;Soybean oil;Lard
期刊:
Journal of Traditional and Complementary Medicine
ISSN:
2225-4110
年:
2024
卷:
14
期:
5
页码:
522-533
基金类别:
We would like to thank the National Natural Science Foundation of China (Grant No. 32373079), and the Frontier Key Science and Technology Research in the Pig Industry (Grant No. 2019xny-js044). We would also like to thank Bullet Edits Limited for the linguistic editing and proofreading of the manuscript. We would like to thank the National Natural Science Foundation of China (Grant No. 32373079 ), and the Frontier Key Science and Technology Research in the Pig Industry (Grant No. 2019xny-js044 ). We would also like to thank Bullet Edits Limited for the linguistic editing and proofreading of the manuscript.
机构署名:
本校为第一且通讯机构
院系归属:
动物科学技术学院
动物医学院
摘要:
Neuroinflammation is considered the principal pathogenic mechanism underlying neurodegenerative diseases, and the incidence of brain disorders is closely linked to dietary fat consumption and intestinal health. To investigate this relationship, 60 8-week-old C57BL/6J mice were subjected to a 20-week dietary intervention, wherein they were fed lard and soybean oil, each at 15% and 35% fat energy. At a dietary fat energy level of 35%, inflammation was observed in both the soybean oil and lard groups. Nevertheless, inflammation was more pronounced...

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