National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81501708, 81220279, 81370252, 81770306, 81471868]; Province Natural Science Foundation of Hunan [2018JJ2547]
机构署名:
本校为其他机构
院系归属:
食品科学技术学院
摘要:
Nucleolin is a multifunctional phosphoprotein and is involved in protecting from myocardial ischemia/reperfusion (I/R) injury. The function of nucleolin is regulated by posttranslational modifications, including phosphorylation and glycosylation. To study whether phosphorylation of nucleolin (P-nucleolin) was involved in the protection from myocardial I/R injury. We investigated the expression pattern of P-nucleolin (Thr-76 and 84) in hearts subjected to I/R injury, or rat cardiac myoblast cells (H9C2) subjected to hydrogen peroxide (H 2 O 2 ). The results showed that the expression of P-nucle...