期刊论文

Jiang, Bimei

英文

JOURNAL OF CELLULAR PHYSIOLOGY

0021-9541

2019

234

4

4044-4053

10.1002/jcp.27191

National Natural Science Foundation of China, Grant/Award Numbers: 81501708, 81220279, 81370252, 81770306, 81471868; Province Natural Science Foundation of Hunan, Grant/Award Number: 2018JJ2547 This study was supported by funding from the National Natural Science Foundation of China, Grant/Award Numbers: 81501708, 81220279, 81370252, 81770306, 81471868；Province Natural Science Foundation of Hunan, Grant/Award Number: 2018JJ2547. The authors are thankful to professor Michael B. Kastan (St. Jude Children’s Research Hospital, USA) for his gift of nucleolin plasmid. This study was supported by funding from the National Natural Science Foundation of China, Grant/Award Numbers: 81501708, 81220279, 81370252, 81770306, 81471868; Province Natural Science Foundation of Hunan, Grant/Award Number: 2018JJ2547. The authors are thankful to professor Michael B. Kastan (St. Jude Children?s Research Hospital, USA) for his gift of nucleolin plasmid.

本校为其他机构

Nucleolin is a multifunctional phosphoprotein and is involved in protecting from myocardial ischemia/reperfusion (I/R) injury. The function of nucleolin is regulated by posttranslational modifications, including phosphorylation and glycosylation. To study whether phosphorylation of nucleolin (P-nucleolin) was involved in the protection from myocardial I/R injury. We investigated the expression pattern of P-nucleolin (Thr-76 and 84) in hearts subjected to I/R injury, or rat cardiac myoblast cells (H9C2) subjected to hydrogen peroxide (H 2 O 2 ). The results showed that the expression of P-nucle...