Integrative Genomics and Phenotypic Profiling Reveal Lacticplantibacillus plantarum BGI-N6 as a Multifunctional Candidate for Dermatological Probiotic Development

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成果类型：

期刊论文

作者：

Wang, Jinhong;Xu, Xiaowei;Wen, Yangfeng;Wei, Benliang;Chen, Junke;...

通讯作者：

Zhong, YY;Zou, YQ

作者机构：

[Wang, Jinhong; Cai, Sihang; Chen, Junke; Wu, Zhinan; Wang, Mengmeng; Wen, Yangfeng] BGI Res, Shenzhen, Peoples R China.

[Wang, Jinhong] Southwest Univ, Coll Life Sci, Chongqing, Peoples R China.

[Zhong, Yiyi; Wei, Benliang; Zhang, Haifeng; Xu, Xiaowei; Liu, Yanhong] BGI Precis Nutr, Shenzhen, Peoples R China.

[Wen, Yangfeng] Hunan Agr Univ, Coll Plant Protect, Changsha, Peoples R China.

[Chen, Junke] South China Normal Univ, Coll Life Sci, Guangzhou, Peoples R China.

通讯机构：

[Zou, YQ ; Zhong, YY ] B

BGI Precis Nutr, Shenzhen, Peoples R China.

BGI Res, Shenzhen Engn Lab Detect & Intervent Human Intesti, Shenzhen, Peoples R China.

BGI Res, State Key Lab Genome & Multiom Technol, Shenzhen, Peoples R China.

语种：

英文

关键词：

antioxidant activity;complete genome;enzyme activity inhibition;Lactiplantibacillus plantarum;phenotypic analysis;skin health

期刊：

FASEB JOURNAL

ISSN：

0892-6638

年：

2025

卷：

期：

页码：

e70979

DOI：

10.1096/fj.202501440R

基金类别：

This work was supported by National Natural Science Foundation of China under Grant Agreement, KCXFZ20240903094006009 : CY20241202124801003. Yuanqiang Zou will handle the correspondence of the article at all stages of the review and publication process, as well as postpublication. Jinhong Wang and Xiaowei Xu contributed equally to this work.

机构署名：

本校为其他机构

院系归属：

植物保护学院

摘要：

Probiotics and postbiotics are recognized for their potential to benefit skin health, and complete genome analysis serves as a pivotal tool to accelerate the exploration of probiotic functionalities. To investigate this relationship, this study aimed to elucidate the skin-promoting potential of Lactiplantibacillus plantarum BGI-N6 (BGI-N6) through integrated genomic analysis and phenotypic analysis. Results indicated that the high-precision complete genome of BGI-N6 comprises 3 257 641 bases with a 45% GC content and 3030 CDSs, involving mult...

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Integrative Genomics and Phenotypic Profiling Reveal Lacticplantibacillus plantarum BGI-N6 as a Multifunctional Candidate for Dermatological Probiotic Development

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