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Motivational deficits in effort-based decision making in individuals with subsyndromal depression, first-episode and remitted depression patients

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成果类型:
期刊论文
作者:
Yang, Xin-Hua;Huang, Jia;Zhu, Cui-Ying;Wang, Ye-Fei;Cheung, Eric F. C.;...
通讯作者:
Xie, Guang-rong
作者机构:
[Yang, Xin-Hua; Xie, Guang-rong; Wang, Ye-Fei] Cent South Univ, Natl Technol Inst Psychiat, Xiangya Hosp 2, Mental Hlth Inst,Key Lab Psychiat & Mental Hlth H, Changsha 410011, Hunan, Peoples R China.
[Yang, Xin-Hua; Zhu, Cui-Ying] Hunan Agr Univ, Coll Business, Changsha, Hunan, Peoples R China.
[Chan, Raymond C. K.; Huang, Jia] Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China.
[Cheung, Eric F. C.] Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China.
通讯机构:
[Xie, Guang-rong] C
Cent South Univ, Natl Technol Inst Psychiat, Xiangya Hosp 2, Mental Hlth Inst,Key Lab Psychiat & Mental Hlth H, Changsha 410011, Hunan, Peoples R China.
语种:
英文
关键词:
Anhedonia;Depression;Effort-based decision-making;Motivation;Reward
期刊:
Psychiatry Research
ISSN:
0165-1781
年:
2014
卷:
220
期:
3
页码:
874-882
基金类别:
The purpose of the study was to assess the willingness to expend effort for a reward during decision-making in individuals with current depression, remitted depression and never-depressed controls on the EEfRT. We hypothesized that depressed individuals would exhibit deficits in their willingness to expend effort for reward and the deficits would be correlated with depression severity. We also hypothesized that participants with anhedonic symptoms would make fewer HC/HR options.
机构署名:
本校为其他机构
院系归属:
商学院
摘要:
Anhedonia is a hallmark symptom of major depressive disorder (MDD). Preliminary findings suggest that anhedonia is characterized by reduced reward anticipation and motivation of obtaining reward. However, relatively little is known about reward-based decision-making in depression. We tested the hypothesis that anhedonia in MDD may reflect specific impairments in motivation on reward-based decision-making and the deficits might be associated with depressive symptoms severity. In study 1, individuals with and without depressive symptoms performed the modified version of the Effort Expenditure fo...

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