Melatonin increased antioxidant capacity to ameliorate growth retardation and intestinal epithelial barrier dysfunction in diquat-challenged piglets

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成果类型：

期刊论文

作者：

Zha, Andong;Yan, Jiameng;Li, Junyao;Wang, Jing;Qi, Ming;...

通讯作者：

Liao, P;Chun, G

作者机构：

[Liao, Peng; Zha, Andong; Qi, Ming; Yan, Jiameng; Yin, Yulong] Chinese Acad Sci, Inst Subtrop Agr, Natl Engn Lab Pollut Control & Waste Utilizat Live, Lab Anim Nutr Physiologyand Metab Proc,Key Lab Agr, Changsha, Peoples R China.

[Zha, Andong; Yin, Yulong] Univ Chinese Acad Sci, Beijing, Peoples R China.

[Yan, Jiameng; Yin, Yulong] Huazhong Agr Univ, Coll Anim Sci & Technol, Wuhan, Peoples R China.

[Li, Junyao; Yin, Yulong; Wang, Jing] Hunan Agr Univ, Coll Anim Sci, Changsha, Peoples R China.

[Chun, Guo; Chun, G] Hunan Univ Chinese Med, Hosp 1, Ctr Med Res & Innovat, Changsha, Peoples R China.

通讯机构：

[Liao, P ] C

[Chun, G ] H

Chinese Acad Sci, Inst Subtrop Agr, Natl Engn Lab Pollut Control & Waste Utilizat Live, Lab Anim Nutr Physiologyand Metab Proc,Key Lab Agr, Changsha, Peoples R China.

Hunan Univ Chinese Med, Hosp 1, Ctr Med Res & Innovat, Changsha, Peoples R China.

语种：

英文

关键词：

weaned piglets;melatonin;diquat;growth retardation;intestinal epithelial barrier;antioxidant capacity;stunting

期刊：

Journal of the Science of Food and Agriculture

ISSN：

0022-5142

年：

2024

卷：

104

期：

页码：

2262-2271

DOI：

10.1002/jsfa.13114

基金类别：

National Natural Science Foundation of China; Key projects of Guangxi Natural Science Foundation [U20A2054, 32372926, 31960666]; Fujian Provincial Science and Technology Plan Project [2020JJD130024]; Fujian Provincial Science and Technology Department [2020T3029]; Chinese Academy of Sciences Supporting Project of STS Program; Zhanjiang science and technology planning project [2021T3051]; Local science and technology development fund project of the Central Committee of Guangxi Zhuang Autonomous Region [2021A05025]; Application and industrialization of scientific and technological achievements in Guizhou Province [Gui ke ZY21195054]; Jiangxi Technological Innovation Guidance Plan Project [Qian ke he cheng guo [2022] yi ban 002]; Key R&D Projects in Jiangxi Province [20212BDH81024]; Earmarked fund for China Agriculture Research System [20212BBF63023]; [CARS-35]

机构署名：

本校为其他机构

院系归属：

动物科学技术学院

摘要：

BACKGROUND: Diquat is a common environmental pollutant, which can cause oxidative stress in humans and animals. Diquat exposure causes growth retardation and intestinal damage. Therefore, this study was performed to investigate the effects of melatonin on diquat-challenged piglets. RESULTS: Dietary supplementation with 2 mg kg(-1) melatonin significantly increased the average daily gain and feed conversion rate in piglets. Melatonin increased antioxidant capacity, and improved intestinal epithelial barrier function of duodenum and jejunum in ...

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Melatonin increased antioxidant capacity to ameliorate growth retardation and intestinal epithelial barrier dysfunction in diquat-challenged piglets

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