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Multiple mechanisms collectively mediate tungsten homeostasis and resistance in Citrobacter sp. Lzp2

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成果类型:
期刊论文
作者:
Luo, Zipei;Li, Zhen;Sun, Jing;Shi, Kaixiang;Lei, Ming;...
通讯作者:
Du, HH
作者机构:
[Du, HH; Luo, Zipei; Tie, Boqing; Du, Huihui; Lei, Ming] Hunan Agr Univ, Coll Resources & Environm, Changsha 410127, Peoples R China.
[Li, Zhen] Nanjing Agr Univ, Coll Resources & Environm Sci, Nanjing 210095, Peoples R China.
[Sun, Jing] Chinese Acad Sci, Inst Geochem, State Key Lab Environm Geochem, Guiyang 550081, Peoples R China.
[Shi, Kaixiang] Huazhong Agr Univ, Coll Life Sci & Technol, State Key Lab Agr Microbiol, Wuhan 430070, Peoples R China.
通讯机构:
[Du, HH ] H
Hunan Agr Univ, Coll Resources & Environm, Changsha 410127, Peoples R China.
语种:
英文
关键词:
Homeostasis;Microorganism;Resistance;Transcriptome;Tungsten
期刊:
Journal of Hazardous Materials
ISSN:
0304-3894
年:
2023
卷:
448
页码:
130877
基金类别:
CRediT authorship contribution statement Zipei Luo: Methodology, Software, Formal analysis, Investigation, Visualization, Writing – original draft; Zhen Li: Writing – review & editing; Jing Sun: Writing – review & editing; Kaixiang Shi: Writing – review & editing; Ming Lei: Supervision; Boqing Tie: Supervision; Huihui Du: Conceptualization, Methodology, Software, Resources, Data curation, Writing – review & editing, Visualization, Project administration, acquisition.
机构署名:
本校为第一且通讯机构
院系归属:
资源环境学院
摘要:
Tungsten (W) is an emerging contaminant, and current knowledge on W resistance profiles of microorganisms remains scarce and fragmentary. This study aimed to explore the physiological responses of bacteria under W stress and to resolve genes and metabolic pathways involved in W resistance using a transcriptome expression profiling assay. The results showed that the bacterium Citrobacter sp. Lzp2, screened from W-contaminated soil, could tolerate hundreds of mM W(VI) with a 50% inhibiting concentration of ∼110mM. To cope with W stress, Citrobac...

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