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Preparative Separation of High-Purity Dihydroartemisinic Acid from Artemisinin Production Waste by Combined Chromatography

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成果类型:
期刊论文
作者:
Liu, Shuoqian;Ferreira, Jorge Freire da Silva;Tian, Dongming;Tang, Yuwei;Liu, Liping;...
通讯作者:
Tian, Na
作者机构:
[Tian, Na; Liu, Zhonghua; Liu, Shuoqian; Liu, Liping; Tang, Yuwei] Hunan Agr Univ, Dept Tea Sci, Coll Hort & Hardening, Changsha 410128, Hunan, Peoples R China.
[Tian, Dongming; Liu, Zhonghua; Liu, Shuoqian; Yang, Wei] Natl Res Ctr Engn Technol Utilizat Funct Ingredie, Changsha 410128, Hunan, Peoples R China.
[Ferreira, Jorge Freire da Silva] USDA ARS, US Salin Lab, Riverside, CA 92507 USA.
通讯机构:
[Tian, Na] H
Hunan Agr Univ, Dept Tea Sci, Coll Hort & Hardening, Changsha 410128, Hunan, Peoples R China.
语种:
英文
关键词:
anion-exchange resin;Artemisia annua L.;artemisinin production waste;dihydroartemisinic acid;silica-gel chromatography
期刊:
CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN:
0009-2363
年:
2018
卷:
66
期:
3
页码:
319-326
基金类别:
National Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31270335, 31501367]; International Science & Technology Cooperation Program of China [2014DFA32160]
机构署名:
本校为第一且通讯机构
院系归属:
园艺园林学院
摘要:
In order to make full use of artemisinin production waste and thus to reduce the production cost of artemisinin, we developed an efficient and scalable method to isolate high-purity dihydroartemisinic acid from artemisinin production waste by combining anion-exchange resin with silica-gel column chromatography. The adsorption and desorption characteristics of dihydroartemisinic acid on 10 types of anion-exchange resin were investigated, and the results showed that the 717 anion-exchange resin exhibited the highest capacity of adsorption and des...

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