UPLC–QQQ–MS/MS-based widely targeted metabolomic analysis, antioxidant and α-glucosidase inhibitory activities of mulberry leaves processed by solid-state fermentation

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成果类型：

期刊论文

作者：

Chen, Yulian;Liu, Chunming;Yang, Fan;Chen, Hui;Yang, Chenghongwang;...

通讯作者：

Xiao, DF;Xiao, Y

作者机构：

[Yang, Fan; Xiao, Dingfu; Liu, Chunming; Chen, Yulian] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Peoples R China.

[Chen, Hui; Xiao, Yu; Xiao, Y; Yang, Chenghongwang; Fan, Ziyi] Hunan Agr Univ, Coll Food Sci & Technol, Changsha 410128, Peoples R China.

[Xiao, Yu] Hunan Agr Univ, Coll Hort, Key Lab, Minist Educ Tea Sci, Changsha 410128, Peoples R China.

通讯机构：

[Xiao, Y ; Xiao, DF ] H

Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Peoples R China.

Hunan Agr Univ, Coll Food Sci & Technol, Changsha 410128, Peoples R China.

语种：

英文

关键词：

Mulberry leaves;Solid-state fermentation;Widely targeted metabolomic analysis;Metabolite profiling;Biological activity

期刊：

LWT

ISSN：

0023-6438

年：

2023

卷：

188

页码：

115351

DOI：

10.1016/j.lwt.2023.115351

基金类别：

Earmarked Fund for China Agriculture Research System [CARS-37]; National Natural Science Foundation of China [32302611]; Key Research and Development Program of Hunan Province [2023NK2025]; Science Research Project of Education Department of Hunan Province [22C0108]

机构署名：

本校为第一且通讯机构

院系归属：

园艺园林学院

动物科学技术学院

食品科学技术学院

摘要：

Mulberry leaves contain various bioactive constituents and are widely used as traditional medicine and food in Asia. In this study, mulberry leaves were processed by solid-state fermentation (SSF) using a mixture microbial of Lactobacillus plantarum, Candida utilis, Trichoderma koningii, and Bacillus cereus. The effects of SSF on the metabolite profile, antioxidant activity, and alpha-glucosidase inhibitory activity (GIA) of mulberry leaves were investigated. UPLC-QQQ-MS/MS-based widely targeted metabolomic analysis showed the detection of 11 classes of metabolites. SSF drastically influenced ...

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UPLC–QQQ–MS/MS-based widely targeted metabolomic analysis, antioxidant and α-glucosidase inhibitory activities of mulberry leaves processed by solid-state fermentation

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