Enzymatic hydrolysis of cassava leaf proteins unlocks antioxidant and therapeutic peptides: Alcalase-derived bioactives target oxidative stress pathways

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成果类型：

期刊论文

作者：

Zhang, Jinquan;Fang, Yusi;Zhang, Zuoda;Yu, Houmei;Lin, Liming;...

通讯作者：

Song, Y;Wang, Qinfei;Zhang, ZW

作者机构：

[Fang, Yusi; Song, Yong; Zhang, Jinquan] Hunan Agr Univ, Coll Hort, 1 Nongda Rd, Changsha 410000, Hunan, Peoples R China.

[Zhang, Zhenwen; Lin, Liming; Wang, Qinfei; Zhang, Zuoda; Yu, Houmei; Zhang, Jinquan] Chinese Acad Trop Agr Sci, Trop Crops Genet Resources Inst, Natl R&D Ctr Potato Proc, Haikou 571101, Hainan, Peoples R China.

[Zhang, Zhenwen; Lin, Liming; Wang, Qinfei; Yu, Houmei] Minist Agr Germplasm Resources Conservat & Utiliza, Key Lab, Haikou 571101, Peoples R China.

[Zhang, Zhenwen; Lin, Liming; Wang, Qinfei; Yu, Houmei] Key Lab Trop Crops Germplasm Resources Genet Impro, Haikou 571101, Peoples R China.

[Song, Yong] Yuelushan Lab, Hongqi Rd, Changsha 410128, Hunan, Peoples R China.

通讯机构：

[Song, Y ] H

[Wang, QF; Zhang, ZW ] C

Hunan Agr Univ, Coll Hort, 1 Nongda Rd, Changsha 410000, Hunan, Peoples R China.

Chinese Acad Trop Agr Sci, Trop Crops Genet Resources Inst, 4 Xueyuan Rd, Haikou 571101, Peoples R China.

语种：

英文

关键词：

Cassava leaves;Bioactive peptides;Network pharmacology;Molecular docking

期刊：

Food Chemistry

ISSN：

0308-8146

年：

2025

卷：

491

页码：

145280

DOI：

10.1016/j.foodchem.2025.145280

基金类别：

Agriculture Research System of China [CARS-11-HNSY, CARS-11-HNZZW]; National Key Research and Development Program of China [2023YFD1000600]

机构署名：

本校为第一且通讯机构

院系归属：

园艺园林学院

摘要：

Cassava leaves, often discarded as agricultural byproduct, are a nutrient-dense yet underutilized protein source, containing 38 % proteins by dried weight. This study investigates the potential of cassava leaf proteins as a sustainable alternative to conventional protein sources through enzymatic hydrolysis. Bioactive peptides extracted during hydrolysis significantly improve the protein's nutritional profile and exhibited diverse biological activities. Analysis revealed a notable increase in essential amino acids, comprising ~40 % of total a...

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Enzymatic hydrolysis of cassava leaf proteins unlocks antioxidant and therapeutic peptides: Alcalase-derived bioactives target oxidative stress pathways

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