期刊论文

Xiao, Shunyuan;Xiong, Xingyao

英文

PLANT CELL

1040-4651

2016

28

5

1108-1126

10.1105/tpc.15.00880

We thank Ryan Cooper for maintaining the plantgrowth facility, Jane Parker for the eds1-2 mutant in the Col-0 background, June Kwak for seeds of rbohD, rbohF, and rbohD rbohF mutants, Jin-Xing Lin for the GFP-RbohD DNA construct, Xinnan Wang and Ryan Kwak for mutant screening, and particularly Ralf Mendel for guidance in biochemical characterization of XDH1 variants. This project was supported by a National Science Foundation grant (IOS-1146589 and IOS-1457033) to S.X., a collaborative grant from Hunan Agricultural University, China to X.M., and Deutsche Forschungsgemeinschaft grants (Bi 1075/4-1 and Bi 1075/5-1) to F.B.

本校为通讯机构

While plants produce reactive oxygen species (ROS) for stress signaling and pathogen defense, they need to remove excessive ROS induced during stress responses in order to minimize oxidative damage. How can plants fine-tune this balance and meet such conflicting needs? Here, we show that XANTHINE DEHYDROGENASE1 (XDH1) in Arabidopsis thaliana appears to play spatially opposite roles to serve this purpose. Through a large-scale genetic screen, we identified three missense mutations in XDH1 that impair XDH1’s enzymatic functions and consequently ...