DNA is use to precisely control the morphology of prussian blue nanoparticles (PBNPs) via electrostatic interaction‐mediated self‐assembly of inorganic ions and protonated DNA for the first time. The flower‐like PBNPs (PB nanoflowers) mediated by 30‐mer Oligo‐C exhibit excellent photothermal properties, mimetic peroxidase activity, biorecognition ability, photo‐fenton catalytic performance and light scattering, and is expected to be widely used in biosensing, catalysis and imaging. Abstract While shapes and surface properties of nanomater...