期刊论文

Wen, Lixin;Wu, Jing

英文

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

1095-6670

2020

34

2

e22428

10.1002/jbt.22428

We would like to extend our gratitude to the platform and funding provided by the National Key R&D Program of China, Scientific Research Project of Hunan Provincial Education Department, China Postdoctoral Science Foundation, College of Veterinary Medicine, Hunan Agricultural University, and Hunan Collaborative Innovation Center of Animal Production Safety. We would like to extend our gratitude to the platform and funding provided by the National Key R&D Program of China, Scientific Research Project of Hunan Provincial Education Department, China Postdoctoral Science Foundation, College of Veterinary Medicine, Hunan Agricultural University, and Hunan Collaborative Innovation Center of Animal Production Safety.

本校为第一机构

The aim of this study is to confirm the toxic effect of phenylethyl isothiocyanate (PEITC) on porcine kidney cells (PK-15) and explore the effect of oxidative damage mediated by reactive oxygen species (ROS) induced by PEITC in PK-15 cells. Porcine kidney cell line (PK-15) was treated with PEITC (2, 5, and 10 µM) for 24 hours, and the oxidative damage mediated by PEITC through ROS was investigated. The survival rate of PK-15 cells decreased in a dose-dependent manner after the treatment of PEITC in a dose-dependent manner. A high concentration...