Protective effects of kaempferol against endothelial damage by an improvement in nitric oxide production and a decrease in asymmetric dimethylarginine level

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Xiao, Hong-Bo;Jun-Fang;Lu, Xiang-Yang;Chen, Xiao-jun;Chao-Tan;...

通讯作者：

Sun, Zhi-Liang

作者机构：

[Xiao, Hong-Bo; Sun, Zhi-Liang; Chao-Tan; Chen, Xiao-jun] Hunan Agr Univ, Coll Vet Med, Changsha 410128, Hunan, Peoples R China.

[Jun-Fang] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Hunan, Peoples R China.

[Lu, Xiang-Yang] Hunan Agr Bioengn Res Inst, Changsha 410128, Hunan, Peoples R China.

[Xiao, Hong-Bo; Sun, Zhi-Liang; Chen, Xiao-jun] Hunan Vet Drug Engn Technol Ctr, Changsha 410128, Hunan, Peoples R China.

通讯机构：

[Sun, Zhi-Liang] H

Hunan Agr Univ, Coll Vet Med, Changsha 410128, Hunan, Peoples R China.

语种：

英文

关键词：

Kaempferol;Endothelium;Nitric oxide;Asymmetric dimethylarginine;Lysophosphatidylcholine;Apolipoprotein E-deficient mouse;Human umbilical vein endothelial cell

期刊：

European Journal of Pharmacology

ISSN：

0014-2999

年：

2009

卷：

616

期：

1-3

页码：

213-222

DOI：

10.1016/j.ejphar.2009.06.022

机构署名：

本校为第一且通讯机构

院系归属：

动物医学院

生物科学技术学院

摘要：

Previous investigations have shown that asymmetric dimethylarginine (ADMA) inhibits nitric oxide (NO) synthases (NOS) and that ADMA is a risk factor for endothelial dysfunction. The objective of this study was to investigate the protective effect of kaempferol, a naturally occurring flavonoid antioxidant agent, against endothelial damage and the mechanisms involved. The experiments were performed in aorta and plasma from C57BL/6J control and apolipoprotein E-deficient (ApoE-/-) mice treated or not with kaempferol (50 or 100 mg/kg, intragastrica...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Protective effects of kaempferol against endothelial damage by an improvement in nitric oxide production and a decrease in asymmetric dimethylarginine level

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问