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Chemoselective metal-free indole arylation with cyclohexanones

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成果类型:
期刊论文
作者:
Lu, Chaogang;Huang, Huawen*;Tuo, Xiaolong;Jiang, Pingyu;Zhang, Feng;...
通讯作者:
Huang, Huawen;Deng, Guo-Jun
作者机构:
[Jiang, Pingyu; Deng, Guo-Jun; Huang, Huawen; Deng, GJ; Lu, Chaogang; Tuo, Xiaolong; Zhang, Feng] Xiangtan Univ, Coll Chem, Minist Educ, Key Lab Environm Friendly Chem & Applicat, Xiangtan 411105, Peoples R China.
[Zhang, Feng] Hunan Agr Univ, Coll Sci, Changsha 410128, Hunan, Peoples R China.
通讯机构:
[Huang, HW; Deng, GJ] X
Xiangtan Univ, Coll Chem, Minist Educ, Key Lab Environm Friendly Chem & Applicat, Xiangtan 411105, Peoples R China.
语种:
英文
关键词:
Chemical reactions;Arylations;Chemoselective;Cyclohexanones;Elemental sulfur;Metal free;Polycyclic aromatic hydrocarbons
期刊:
Organic Chemistry Frontiers
ISSN:
2052-4110
年:
2019
卷:
6
期:
15
页码:
2738-2743
基金类别:
Support by the National Natural Science Foundation of China (21871226, 21602187), the China Postdoctoral Science Foundation (2018M632976), and the Collaborative Innovation Center of New Chemical Technologies for Environmental Benignity and Efficient Resource Utilization is gratefully acknowledged.
机构署名:
本校为其他机构
院系归属:
理学院
摘要:
Herein, we have revealed elemental sulfur-and iodine reagent-mediated indole C3 arylations using cyclohexanones as the arylating reagent. This protocol provides an efficient gram-scalable access to 3-Arylindole and benzo[4,5]thieno[2,3-b]indole motifs with a broad range of compatible functi...

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