Clear Genetic Distinctiveness between Human- and Pig-Derived Trichuris Based on Analyses of Mitochondrial Datasets

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成果类型：

期刊论文

作者：

Liu, Guo-Hua*;Gasser, Robin B.;Su, Ang;Nejsum, Peter;Peng, Lifei;...

通讯作者：

Liu, Guo-Hua

作者机构：

[Xu, Min-Jun; Su, Ang; Liu, Guo-Hua; Zhu, Xing-Quan] Chinese Acad Agr Sci, State Key Lab Vet Etiol Biol, Key Lab Vet Parasitol Gansu Prov, Lanzhou Vet Res Inst, Lanzhou, Gansu, Peoples R China.

[Liu, Guo-Hua; Zhu, Xing-Quan] Hunan Agr Univ, Coll Vet Med, Changsha, Hunan, Peoples R China.

[Gasser, Robin B.] Univ Melbourne, Dept Vet Sci, Werribee, Vic 3030, Australia.

[Su, Ang; Lin, Rui-Qing] S China Agr Univ, Coll Vet Med, Guangzhou, Guangdong, Peoples R China.

[Nejsum, Peter] Univ Copenhagen, Dept Vet Dis Biol, Frederiksberg, Denmark.

通讯机构：

[Liu, Guo-Hua] C

Chinese Acad Agr Sci, State Key Lab Vet Etiol Biol, Key Lab Vet Parasitol Gansu Prov, Lanzhou Vet Res Inst, Lanzhou, Gansu, Peoples R China.

语种：

英文

关键词：

Trichuris;Swine;Human genomics;Nucleotide sequencing;Trichuriasis;Phylogenetic analysis;Transfer RNA;Mammalian genomics

期刊：

PLOS NEGLECTED TROPICAL DISEASES

ISSN：

1935-2735

年：

2012

卷：

期：

页码：

e1539

DOI：

10.1371/journal.pntd.0001539

基金类别：

Program for Outstanding Scientists in Agricultural Research; State Key Laboratory of Veterinary Etiological Biology; Lanzhou Veterinary Research Institute; Chinese Academy of Agricultural Sciences [SKLVEB2011KFKT004, SKLVEB2011KFKT011, SKLVEB2010KFKT009, SKLVEB2009KFKT008, SKLVEB2011KFKT010]; Yunnan Provincial Program for Introducing High-level Scientists [2009CI125]; Australian Research Council (ARC)Australian Research Council

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本校为其他机构

院系归属：

动物医学院

摘要：

Author Summary Trichuriasis is a neglected tropical disease (NTD) caused by parasitic nematodes of the genus Trichuris (Nematoda), causing significant human and animal health problems as well as considerable socio-economic consequences world-wide. Although Trichuris species are considered to be relatively host specific, there has been significant controversy as to whether Trichuris infecting humans (recognized as T. trichiura) is a distinct species from that found in pigs (recognized as T. suis), or not. In the present study, we sequenced, annotated and compared the complete mitochondrial geno...

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Clear Genetic Distinctiveness between Human- and Pig-Derived Trichuris Based on Analyses of Mitochondrial Datasets

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