Systematic identification of compounds in Macleaya microcarpa by HPLC-Q/TOF-MS/MS combined with mass spectral fragmentation behavior of Macleaya alkaloids.
Hunan Provincial Natural Science Foundation of ChinaNatural Science Foundation of Hunan Province [2017JJ1017]; National Key R&D Program of China [2017YFD0501500]
机构署名：
本校为第一且通讯机构
院系归属：
动物医学院
摘要：
RATIONALE: Macleaya microcarpa (Maxim.) Fedde is a genus of Macleaya belonging to papaveraceae family. Benzylisoquinoline alkaloids are considered the main bioactive constituents of M. microcarpa. METHODS: Using HPLC-Q/TOF-MS/MS we identified the benzylisoquinoline alkaloids in the aerial parts of M. microcarpa at early flowering stage. Target profiling and identification of benzylisoquinoline alkloids in the extracted samples from fresh aerial parts of M. microcarpa were exclusively based on a personal accurate mass database of known compounds combined with the mass spectral fragmentation beh...
