期刊论文

Ligui Xiong<&wdkj&>Zhonghua Liu<&wdkj&>Yushun Gong

英文

食品科学与人类健康

2213-4530

2023

12

6

2297-2305

10.1016/j.fshw.2023.03.033

supported by the National Natural Science Foundation of China [No. 31801547]； Some C. elegans strains were provided by CGC， which is funded by the NIH Office of Research Infrastructure Programs；

本校为第一机构

Fuzhuan brick-tea (FZT) has long been consumed for its supposed weight loss and lipid-lowering benefits. In this study, we show that the regulation of fat storage in Caenorhabditis elegans from a water extract of FZT was affected by cholesterol levels. We found that FZT significantly decreased fat storage under normal cholesterol levels or in a cholesterol-free diet, while lipid accumulation was increased for a high cholesterol diet. Moreover, this mechanism may involve the conserved sterol regulatory element-binding protein (SREBP)/ mediator-15 (MDT-15) signaling pathway and the nuclear hormo...

Fuzhuan brick-tea(FZT)has long been consumed for its supposed weight loss and lipid-lowering benefi ts.In this...展开更多 Fuzhuan brick-tea(FZT)has long been consumed for its supposed weight loss and lipid-lowering benefi ts.In this study,we show that the regulation of fat storage in Caenorhabditis elegans from a water extract of FZT was affected by cholesterol levels.We found that FZT signifi cantly decreased fat storage under normal cholesterol levels or in a cholesterol-free diet,while lipid accumulation was increased for a high cholesterol ...