Identification of the Impurities in Bopu Powder (R) and Sangrovit (R) by LC-MS Combined with a Screening Method

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Dong, Zhuang;Liu, Mengting;Zhong, Xiaohong;Ou, Xiaoyong;Yun, Xuan;...

作者机构：

[Yun, Xuan; Qing, Zhixing; Ren, Shurui; Liu, Mengting; Zeng, Jianguo; Dong, Zhuang; Ou, Xiaoyong; Wang, Mingcan] Hunan Agr Univ, Hunan Key Lab Tradit Chinese Vet Med, Changsha 410128, Peoples R China.

[Zhong, Xiaohong; Dong, Zhuang] Hunan Agr Univ, Coll Hort, Changsha 410128, Peoples R China.

[Yun, Xuan; Qing, Zhixing; Liu, Mengting; Zeng, Jianguo; Ou, Xiaoyong] Hunan Agr Univ, Coll Vet Med, Changsha 410128, Peoples R China.

语种：

英文

关键词：

impurity analysis;Bopu powder (R);Sangrovit (R);isoquinoline alkaloids;screening method;LC-MS

期刊：

Molecules

ISSN：

1420-3049

年：

2021

卷：

期：

页码：

3851

DOI：

10.3390/molecules26133851

基金类别：

National Key R&D Program of China [2017YFD0501500]; Hunan Provincial Key Research and Development Project [2020NK2031]; Special Funds for Development of Local Science and Technology from Central Government [2019XF5067]

机构署名：

本校为第一机构

院系归属：

园艺园林学院

动物医学院

摘要：

Bopu powder (R) and Sangrovit (R) were developed from Macleaya cordata and are widely used in agriculture and animal husbandry, but their impurities have been rarely reported in the literature. Impurity analysis is of great importance to the quality and safety of veterinary drugs. In this study, high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (HPLC-Q-TOF-MS) combined with a screening method was used to screen and characterize the impurities in Bopu powder (R) and Sangrovit (R). A total of 58 impurities were screened from Bopu powder (R) and Sangrovit (R) usin...

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Identification of the Impurities in Bopu Powder (R) and Sangrovit (R) by LC-MS Combined with a Screening Method

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