High fischer ratio Oligo-peptides are small peptides (or oligo-peptide) mixture system composed with 2 to 9 amino acids. F value is the molar ratio of branched-chain amino acids (BCAA: Val, Ile, Leu) and aromatic amino acids (AAA: Trp, Tyr, Phe) in the mixture. Because of their unique amino acid composition and physiological function, high fischer ratio Oligo-peptides are given high degree of attention in food and pharmaceutical industry. This paper reviewed physiological function and the latest technology of high fischer ratio oligo-pe...