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Imbalanced spontaneous brain activity in orbitofrontal-insular circuits in individuals with cognitive vulnerability to depression

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成果类型:
期刊论文
作者:
Zhang, Xiaocui;Di, Xin;Lei, Hui;Yang, Juan;Xiao, Jing;...
通讯作者:
Yao, Shuqiao
作者机构:
[Zhang, Xiaocui; Wang, Xiang; Yao, Shuqiao] Cent S Univ, Xiangya Hosp 2, Inst Med Psychol, Changsha, Hunan, Peoples R China.
[Di, Xin] New Jersey Inst Technol, Dept Biomed Engn, Newark, NJ 07102 USA.
[Lei, Hui] Hunan Agr Univ, Coll Educ, Changsha, Hunan, Peoples R China.
[Yang, Juan] Hainan Med Coll, Dept Psychol, Haikou, Hainan, Peoples R China.
[Xiao, Jing] Capital Normal Univ, Beijing Key Lab Learning & Cognit, Beijing, Peoples R China.
通讯机构:
[Yao, Shuqiao] C
Cent S Univ, Xiangya Hosp 2, Inst Med Psychol, Changsha, Hunan, Peoples R China.
语种:
英文
关键词:
adult;amplitude of low frequency fluctuation;Article;Center for Epidemiological Studies Depression Scale;Cognitive Style Questionnaire;cognitive vulnerability to depression;controlled study;correlation analysis;electroencephalogram;female;functional magnetic resonance imaging;fusiform gyrus;hopelessness;human;insula;major clinical study;major depression;male;orbital cortex;priority journal;psychometry;questionnaire;adolescent;brain cortex;case control study;cognition;cross-sectional study;major depression;neuroimaging;nuclear magnetic resonance imaging;pathophysiology;physiology;prefrontal cortex;temporal lobe;young adult;Adolescent;Case-Control Studies;Cerebral Cortex;Cognition;Cross-Sectional Studies;Depressive Disorder, Major;Female;Humans;Magnetic Resonance Imaging;Male;Neuroimaging;Prefrontal Cortex;Temporal Lobe;Young Adult
期刊:
Journal of Affective Disorders
ISSN:
0165-0327
年:
2016
卷:
198
页码:
56-63
机构署名:
本校为其他机构
院系归属:
教育学院
摘要:
Background The hopelessness theory of depression posits that individuals with negative cognitive styles are at risk of developing depression following negative life events. The purpose of this work was to examine whether individuals with cognitive vulnerability to depression (CVD) exhibit similar spontaneous brain activity patterns as compared to patients with major depressive disorder (MDD). Methods Subjects with CVD (N=32), drug-naïve first-episode patients with major depressive disorder (N=32), and sex-, age- and education-matched healthy c...

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