Multi-spectroscopies and molecular docking insights into the interaction mechanism and antioxidant activity of astaxanthin and β-lactoglobulin nanodispersions

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成果类型：

期刊论文

作者：

Liu, Zhi-Wei;Zhou, Ying-Xue;Wang, Lang-Hong;Ye, Zhang;Liu, Lian-Jie;...

通讯作者：

Zhi-Wei Liu<&wdkj&>Rana Muhammad Aadil

作者机构：

[Zhou, Ying-Xue; Liu, Zhi-Wei; Liu, Lian-Jie; Ye, Zhang; Wang, Feng] Hunan Agr Univ, Coll Food Sci & Technol, Changsha 410128, Peoples R China.

[Wang, Lang-Hong] Northwest Univ, Coll Food Sci & Technol, Xian 710069, Peoples R China.

[Cheng, Jun-Hu] South China Univ Technol, Sch Food Sci & Engn, Guangzhou 510640, Peoples R China.

[Bekhit, Alaa El-Din] Univ Otago, Dept Food Sci, Dunedin 9054, New Zealand.

[Aadil, Rana Muhammad] Univ Agr Faisalabad, Natl Inst Food Sci & Technol, Faisalabad 38000, Pakistan.

通讯机构：

[Zhi-Wei Liu] C

[Rana Muhammad Aadil] N

College of Food Science and Technology, Hunan Agricultural University, Changsha, 410128, China<&wdkj&>National Institute of Food Science and Technology, University of Agriculture, Faisalabad, 38000, Pakistan

语种：

英文

关键词：

Astaxanthin;beta-lactoglobulin;Molecular docking;Interaction;Antioxidant;Nanodispersion

期刊：

Food Hydrocolloids

ISSN：

0268-005X

年：

2021

卷：

117

页码：

106739

DOI：

10.1016/j.foodhyd.2021.106739

基金类别：

Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2019JJ50266]

机构署名：

本校为第一机构

院系归属：

食品科学技术学院

摘要：

In this study, interaction mechanism of astaxanthin (AST) with beta-lactoglobulin (beta-La) nanodispersions that were prepared by emulsification-evaporation method was investigated using multi-spectroscopies and molecular docking. Further, the antioxidant activity of the resultant nanodispersions was evaluated. The AST was successfully bound to the beta-La and spontaneous interaction between beta-La and AST complex was established. Hydrophobic interactions between beta-La and AST were the dominant force that maintained the binding affinity. The nanodispersions were characterized by a static qu...

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Multi-spectroscopies and molecular docking insights into the interaction mechanism and antioxidant activity of astaxanthin and β-lactoglobulin nanodispersions

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