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Characterization of grass carp spleen transcriptome during GCRV infection

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成果类型:
期刊论文
作者:
Xu, B. H.;Zhong, L.;Liu, Q. L.;Xiao, T. Y.*;Su, J. M.;...
通讯作者:
Xiao, T. Y.
作者机构:
[Zhong, L.; Chen, J.; Wang, H. Q.; Xiao, T. Y.; Liu, Q. L.; Chen, K. J.; Dai, Y. J.; Xu, B. H.] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha, Hunan, Peoples R China.
[Su, J. M.] Hunan Agr Univ, Coll Anim Vet & Med, Changsha, Hunan, Peoples R China.
通讯机构:
[Xiao, T. Y.] H
Hunan Agr Univ, Coll Anim Sci & Technol, Changsha, Hunan, Peoples R China.
语种:
英文
关键词:
Gene ontology;Grass carp hemorrhage;Grass carp reovirus;High-throughput sequencing;KEGG;Transcriptome sequencing
期刊:
Genetics and Molecular Research
ISSN:
1676-5680
年:
2016
卷:
15
期:
2
基金类别:
We would like to thank our researchers for their hard work, and reviewers for their valuable advice. Research supported by the National Natural Science Foundation of China (#31272652), the National High Technology Research and Development Program of China (#2011AA100404), the National Natural Science Foundation of China (#31402289), and the National Technology System for Conventional Freshwater Fish Industries of China Agriculture Research System (#CARS-46-42).
机构署名:
本校为第一且通讯机构
院系归属:
动物科学技术学院
动物医学院
摘要:
The aim of the study was to investigate the grass carp hemorrhagic infection pathway and its key-related genes. Grass carp reovirus (GCRV) might cause hemorrhagic disease in grass carps. Healthy grass carp fingerlings (N = 60) were divided into control and infected groups. Fish in the control group were intraperitoneally (ip) injected with 0.6% fish physiological saline, the infected group received 5,000,000 50% tissue culture infective doses of GCRV 873 standard strain, a double-stranded RNA (dsRNA) virus strain, ip, in 0.5 mL. Illumina HiSeq™...

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