期刊论文

Wei-Min He

英文

中国化学快报：英文版

1001-8417

2021

32

6

1907-1910

10.1016/j.cclet.2021.01.021

financial support from Hunan Provincial Natural Science Foundation of China （Nos. 2018JJ3215 and 2019JJ20008）； the Research Foundation of Education Bureau of Hunan Province （No. 18C0147）； Double First-class Construction Project of Hunan Agricultural University （No. SYL2019064）；

本校为第一机构

An efficient and eco-friendly protocol for synthesizing difluoromethylated oxindoles through a visiblelight induced one-pot tandem reaction of N-arylacrylamides, difluoroacetic acid and Ph I（OAc）2 was developed. This reaction proceeded in the absence of any additive, base, metal-catalyst and external photosensitizer, using cheap and easily available CHF2CO2H as the difluoromethylation reagent and bulk biomass-derived 2-Me THF as the sole solvent. 26 Examples of N-arylacrylamide substrates were investigated, and all of them successfully underwent difluoromet...