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Optimal sampling of a population to determine QTL location, variance, and allelic number

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成果类型:
期刊论文
作者:
Wu, XL;Jannink, JL*
通讯作者:
Jannink, JL
作者机构:
[Jannink, JL] Iowa State Univ Sci & Technol, Dept Agron, Ames, IA 50011 USA.
Hunan Agr Univ, Ctr Life Sci Res, Hunan 410128, Peoples R China.
通讯机构:
[Jannink, JL] I
Iowa State Univ Sci & Technol, Dept Agron, Ames, IA 50011 USA.
语种:
英文
期刊:
Theoretical and Applied Genetics
ISSN:
0040-5752
年:
2004
卷:
108
期:
7
页码:
1434-1442
机构署名:
本校为其他机构
院系归属:
生物科学技术学院
摘要:
In a population intended for breeding and selection, questions of interest relative to a specific segregating QTL are the variance it generates in the population, and the number and effects of its alleles. One approach to address these questions is to extract several inbreds from the population and use them to generate multiple mapping families. Given random sampling of parents, sampling strategy may be an important factor determining the power of the analysis and its accuracy in estimating QTL variance and allelic number. We describe appropriate multiple-family QTL mapping methodology and app...

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