PROTECTIVE EFFECTS OF SOLUBLE FIBER FROM UNDARIA PINNATIFIDA ON VASCULAR ENDOTHELIUM IN MICE

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Xiao, Hong-Bo*;Lu, Xiang-Yang;Sun, Zhi-Liang;Hu, Ya-Ping;Bai, Xia;...

通讯作者：

Xiao, Hong-Bo

作者机构：

[Xiao, Hong-Bo; Bai, Xia; Zhang, Ming-Jun.; Chen, Xiao-Jun] Hunan Agr Univ, Coll Vet Med, Changsha 410128, Hunan, Peoples R China.

[Lu, Xiang-Yang] Hunan Agr Univ, Hunan Agr Bioengn Res Inst, Changsha 410128, Hunan, Peoples R China.

[Sun, Zhi-Liang] Hunan Agr Univ, Hunan Vet Drug Engn Technol Ctr, Changsha 410128, Hunan, Peoples R China.

[Hu, Ya-Ping] Hunan Agr Univ, Fac Food Sci & Technol, Changsha 410128, Hunan, Peoples R China.

通讯机构：

[Xiao, Hong-Bo] H

Hunan Agr Univ, Coll Vet Med, Changsha 410128, Hunan, Peoples R China.

语种：

英文

期刊：

Journal of Food Biochemistry

ISSN：

0145-8884

年：

2011

卷：

期：

页码：

1737-1746

DOI：

10.1111/j.1745-4514.2010.00516.x

基金类别：

College of Veterinary Medicine; Hunan Livestock Bureau [BK0717]

机构署名：

本校为第一且通讯机构

院系归属：

动物医学院

食品科学技术学院

生物科学技术学院

摘要：

The objective of this study was to investigate the protective effect of soluble fiber extracted from Undaria pinnatifida (UP) on vascular endothelium and the mechanisms involved. The experiments were performed in aorta and plasma from C57BL/6J control and apolipoprotein E deficient (ApoE-/-) mice treated or not with UP soluble fiber (5 or 10%) for 8 weeks. UP soluble fiber treatment improved endothelium-dependent vasorelaxation, increased the maximal relaxation value, and decreased the half-maximum effective concentration concomitantly with a decrease in asymmetric dimethylarginine (ADMA) and ...

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