期刊论文

中文

精细化工

1003-5214

2022

39

9

1908-1916

10.13550/j.jxhg.20220253

31671858:国家自然科学基金 2019JJ40114:湖南省自然科学基金

本校为第一机构

为解决姜酮酚辛辣刺激性强、口服生物利用度低的问题,采用高压均质技术,以菜籽油为载体油、吐温80为乳化剂,制备了姜酮酚纳米乳液,考察了菜籽油质量分数对乳液粒径、Zeta电位、游离脂肪酸释放率和姜酮酚生物可及率的影响。结果表...展开更多 为解决姜酮酚辛辣刺激性强、口服生物利用度低的问题,采用高压均质技术,以菜籽油为载体油、吐温80为乳化剂,制备了姜酮酚纳米乳液,考察了菜籽油质量分数对乳液粒径、Zeta电位、游离脂肪酸释放率和姜酮酚生物可及率的影响。结果表明,随着菜籽油质量分数的提高,纳米乳液粒径显著增大,Zeta电位无明显变化。各乳液小肠消化阶段游离脂肪酸释放率接近100%,油脂基...

Nanoemulsions loaded with paradol were prepared by high pressure homogenization technology using rapeseed oil as oil phase and Tween 80 as emulsifier to improve the low oral bioavailability and pungent taste associated with paradol.The effects of rapeseed oil mass fract...MORE Nanoemulsions loaded with paradol were prepared by high pressure homogenization technology using rapeseed oil as oil phase and Tween 80 as emulsifier to improve the low oral bioavailability and pungent taste associated with paradol.The effects of rapeseed oil mass fractio...