This work was supported by the Young Scientist Research Foundation of Hunan Educational Committee (Grant No. 10B046) and by the Hunan Committee of Science and Technology, China (Grant No. 2012NK3078).
机构署名:
本校为第一且通讯机构
院系归属:
动物科学技术学院
动物医学院
摘要:
A full-length cDNA clone encoding grass carp (Ctenopharyngodon idellus) α1-microglobulin/bikunin precursor (Ci-AMBP) was isolated by subtracted differential hybridization screening from a liver cDNA library. The deduced amino acid sequence shared approximately 50% sequence identity with its mammalian counterparts, but more than 90% identity with another fish species. AMBPs are the precursors of the plasma glycoproteins α1-microglobulin (α1m) and bikunin. Both peptide structures and their chromosomal organization were well conserved in Ci- AM...