Hijacking of Host Plasminogen by Mesomycoplasma (Mycoplasma) hyopneumoniae via GAPDH: an Important Virulence Mechanism To Promote Adhesion and Extracellular Matrix Degradation

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成果类型：

期刊论文

作者：

Wang, Jiying;Li, Shiyang;Chen, Junhong;Gan, Lanxi;Wang, Jia;...

通讯作者：

Yuan, XM;Yu, YF

作者机构：

[Li, Shiyang; Yuan, Xiaomin; Yuan, XM; Gan, Lanxi; Deng, Zhibang; Wang, Jiying] Hunan Agr Univ, Coll Vet Med, Changsha, Peoples R China.

[Yu, Yanfei; Xiong, Qiyan; Wang, Jia; Li, Shiyang; Yu, YF; Feng, Zhixin; Gan, Lanxi; Wang, Jiying] Jiangsu Acad Agr Sci, Inst Vet Med, Key Lab Vet Biol Engn & Technol, Minist Agr & Rural Affairs, Nanjing, Peoples R China.

[Yu, Yanfei; Xiong, Qiyan; Wang, Jia; Li, Shiyang; Yu, YF; Feng, Zhixin; Gan, Lanxi; Wang, Jiying] Guotai Taizhou Ctr Technol Innovat Vet Biol, Taizhou, Peoples R China.

[Wang, Jiying] Huaihua Polytech Coll, Dept Anim Sci & Technol, Huaihua, Peoples R China.

[Chen, Junhong] Jinling Inst Technol, Sch Anim Sci & Food Engn, Nanjing, Peoples R China.

通讯机构：

[Yu, YF ] J

[Yuan, XM ] H

Hunan Agr Univ, Coll Vet Med, Changsha, Peoples R China.

Jiangsu Acad Agr Sci, Inst Vet Med, Key Lab Vet Biol Engn & Technol, Minist Agr & Rural Affairs, Nanjing, Peoples R China.

Guotai Taizhou Ctr Technol Innovat Vet Biol, Taizhou, Peoples R China.

语种：

英文

关键词：

Mesomycoplasma hyopneumoniae;GAPDH;adhesion;plasminogen;extracellular matrix

期刊：

MICROBIOLOGY SPECTRUM

ISSN：

2165-0497

年：

2023

卷：

期：

页码：

e0021823

DOI：

10.1128/spectrum.00218-23

基金类别：

National Natural Science Foundation of China [32172860, 32102675]; Natural Science Foundation of Hunan Province [2022JJ50321]; Education Department of Hunan Province [22B1055]

机构署名：

本校为第一且通讯机构

院系归属：

动物医学院

摘要：

Mesomycoplasma hyopneumoniae is a specific pathogen of pigs that is the etiological agent of mycoplasmal pneumonia of swine (MPS), which is responsible for substantial economic losses to the swine industry worldwide. The pathogenicity mechanism and possible particular virulence determinants of M. hyopneumoniae are not yet completely elucidated. Mesomycoplasma hyopneumoniae is the etiological agent of mycoplasmal pneumonia of swine (MPS), which causes substantial economic losses to the world's swine industry. Moonlighting proteins are increasingly being shown to play a role in the pathogenic pr...

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Hijacking of Host Plasminogen by Mesomycoplasma (Mycoplasma) hyopneumoniae via GAPDH: an Important Virulence Mechanism To Promote Adhesion and Extracellular Matrix Degradation

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