The wide application of fullerene C60 nanoparticles would inevitably lead to their release into the environment. In order to evaluate the environment risks of C60 and the subsequent effects on ecosystem health, a reliable quantitative methodology of C60 should be established. In this study, a rapid pretreatment method called low-density solvent-based dispersive liquid–liquid micro-extraction (DLLME) combined high-performance liquid chromatography-UV detector (HPLC-UV) was developed to detect C60 in environmental water. In this proposed method,...