Junshanyinzhen tea extract prevents obesity by regulating gut microbiota and metabolic endotoxemia in high-fat diet fed rats

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成果类型：

期刊论文

作者：

Ouyang, Jian;Li, Xiuping;Liu, Changwei;Lu, Danmin;Ouyang, Jie;...

通讯作者：

Huang, Jianan;Liu, ZH

作者机构：

[Ouyang, Jie; Liu, Changwei; Li, Xiuping; Liu, Zhonghua; Huang, Jianan; Ouyang, Jian; Lu, Danmin; Zhou, Fang; Liu, Qi; Huang, JN] Hunan Agr Univ, Key Lab Tea Sci, Minist Educ, Changsha 410128, Peoples R China.

[Ouyang, Jie; Liu, Changwei; Li, Xiuping; Liu, Zhonghua; Huang, Jianan; Ouyang, Jian; Lu, Danmin; Zhou, Fang; Liu, Qi] Hunan Agr Univ, Natl Res Ctr Engn Technol Utilizat Funct Ingredien, Changsha 410128, Peoples R China.

[Ouyang, Jie; Liu, Changwei; Li, Xiuping; Liu, Zhonghua; Huang, Jianan; Ouyang, Jian; Lu, Danmin; Zhou, Fang; Liu, Qi] Hunan Agr Univ, Coinnovat Ctr, Educ Minist Utilizat Bot Funct Ingredients, Changsha 410128, Peoples R China.

[Liu, Zhonghua; Huang, Jianan] Hunan Agr Univ, Key Lab Evaluat & Utilizat Gene Resources Hort Cro, Minist Agr & Rural Affairs, Changsha 410128, Peoples R China.

通讯机构：

[Liu, ZH ; Huang, JN] H

Hunan Agr Univ, Key Lab Tea Sci, Minist Educ, Changsha 410128, Peoples R China.

语种：

英文

关键词：

Junshanyinzhen tea;Obesity;Gut microbiota;Gut barrier function;Metabolic endotoxemia

期刊：

食品科学与人类健康

ISSN：

2213-4530

年：

2024

卷：

期：

页码：

2036-2047

DOI：

10.26599/FSHW.2022.9250169

基金类别：

supported by National Modern Agricultural Industry Technology System(CARS-23) Yueyang Yellow Tea Product Innovation Research Project(2018xny-js053).

机构署名：

本校为第一且通讯机构

院系归属：

园艺园林学院

摘要：

Obesity is associated with gut dysbiosis and metabolic endotoxin. Junshanyinzhen tea extract ( JSTE) reduced fat accumulation and body weight in obese mice. However, the effects and mechanism of JSTE in preventing obesity were unclear. Therefore, we used different doses of JSTE (75, 150 and 300 mg/(kgday)) to evaluate the effect on high-fat diet (HFD)-induced rats under 8 weeks of intervention. Here, our results showed that JSTE could significantly reduce body weight gain, blood lipid levels and fat accumulation, improve fatty damage in liver tissue (P < 0.05). In addition, JSTE increased the ...

摘要(中文)：

Obesity is associated with gut dysbiosis and metabolic endotoxin.Junshanyinzhen tea extract(JSTE)reduced fat a...展开更多 Obesity is associated with gut dysbiosis and metabolic endotoxin.Junshanyinzhen tea extract(JSTE)reduced fat accumulation and body weight in obese mice.However,the effects and mechanism of JSTE in preventing obesity were unclear.Therefore,we used different doses of JSTE(75,150 and 300 mg/(kg·day))to evaluate the effect on high-fat diet(HFD)-induced rats under 8 weeks of intervention.Here,our results showed that JSTE could s...

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Junshanyinzhen tea extract prevents obesity by regulating gut microbiota and metabolic endotoxemia in high-fat diet fed rats

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