The chicken gut metagenome and the modulatory effects of plant-derived benzylisoquinoline alkaloids

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成果类型：

期刊论文

作者：

Huang, Peng;Zhang, Yan;Xiao, Kangpeng;Jiang, Fan;Wang, Hengchao;...

通讯作者：

Zeng, Jianguo;Fan, Wei;Guo, Yuming

作者机构：

[Liu, Xiubin; Huang, Jialu; Liu, Yisong; Zeng, Jianguo; Hu, Nanxi; Cao, Hualiang; Lin, Li; Zeng, Cheng; Qing, Zhixing; Xiao, Kangpeng; Huang, Peng] Hunan Agr Univ, Hunan Key Lab Tradit Chinese Vet Med, Changsha 410128, Hunan, Peoples R China.

[Cao, Hualiang; Xiao, Kangpeng; Huang, Peng] Hunan Agr Univ, Coll Hort & Landscape, Changsha 410128, Hunan, Peoples R China.

[Ren, Yuwei; Wang, Hengchao; Liu, Conghui; Fan, Wei; Jiang, Fan; Huang, Sanwen; Liu, Bo; Zhang, Yan; Yin, Lijuan] Chinese Acad Agr Sci, Agr Genom Inst, Shenzhen 518120, Guangdong, Peoples R China.

[Guo, Yuming; Liu, Dan; Tang, Dazhi] China Agr Univ, Coll Anim Sci & Technol, State Key Lab Anim Nutr, Beijing 100193, Peoples R China.

[Huang, Jialu; Liu, Yisong; Hu, Nanxi; Lin, Li; Yuan, Jingyang; Zeng, Cheng; Su, Xiaogang] Hunan Agr Univ, Coll Vet Med, Changsha 410128, Hunan, Peoples R China.

通讯机构：

[Zeng, Jianguo] H

[Fan, Wei; Guo, Yuming] C

Hunan Agr Univ, Hunan Key Lab Tradit Chinese Vet Med, Changsha 410128, Hunan, Peoples R China.

Chinese Acad Agr Sci, Agr Genom Inst, Shenzhen 518120, Guangdong, Peoples R China.

China Agr Univ, Coll Anim Sci & Technol, State Key Lab Anim Nutr, Beijing 100193, Peoples R China.

语种：

英文

关键词：

Chicken;Gut metagenome;Microbiome;Growth promoter;Benzylisoquinoline alkaloid;Antibiotic;Chlortetracycline

期刊：

Microbiome

ISSN：

2049-2618

年：

2018

卷：

期：

页码：

1-17

DOI：

10.1186/s40168-018-0590-5

基金类别：

This project was supported by grants from the National Key R&D Program of China (2017YFD0501500, 2016YFD0501308 and 2016YFC1200600), the Shenzhen Science and Technology Program (JCYJ20150630165133395), the Fund of Key Laboratory of Shenzhen (ZDSYS20141118170111640), the Agricultural Science and Technology Innovation Program (ASTIP) of the Chinese Academy of Agricultural Sciences, and the Elite Youth Program of the Chinese Academy of Agricultural Sciences.

机构署名：

本校为第一且通讯机构

院系归属：

园艺园林学院

动物科学技术学院

动物医学院

摘要：

Sub-therapeutic antibiotics are widely used as growth promoters in the poultry industry; however, the resulting antibiotic resistance threatens public health. A plant-derived growth promoter, Macleaya cordata extract (MCE), with effective ingredients of benzylisoquinoline alkaloids, is a potential alternative to antibiotic growth promoters. Altered intestinal microbiota play important roles in growth promotion, but the underlying mechanism remains unknown. We generated 1.64 terabases of metagenomic data from 495 chicken intestinal digesta sampl...

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The chicken gut metagenome and the modulatory effects of plant-derived benzylisoquinoline alkaloids

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