The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project

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成果类型：

期刊论文

作者：

Fang, Lingzhao;Teng, Jinyan;Lin, Qing;Bai, Zhonghao;Liu, Shuli;...

通讯作者：

Fang, LZ;Zhang, Z;Zhou, HJ;Liu, GE;Li, JJ;Palmer, AA;Frantz, L

作者机构：

[Lund, Mogens Sando; Gong, Mian; Fang, LZ; Sorensen, Peter; Fang, Lingzhao; Lin, Qing; Sahana, Goutam; Bai, Zhonghao; Liu, Xinfeng; Li, Jing] Aarhus Univ, Ctr Quantitat Genet & Genom, Aarhus, Denmark.

[Li, Jiaqi; Zhang, Zhe; Lin, Qing; Gao, Yahui; Pan, Xiangchun; Gong, Wentao; Teng, Jinyan; Yuan, Xiaolong] South China Agr Univ, State Key Lab Swine & Poultry Breeding Ind, Guangdong Prov Key Lab Agroanim Genom & Mol Breed, Natl Engn Res Ctr Breeding Swine Ind,Coll Anim Sc, Guangzhou, Peoples R China.

[Liu, Shuli; Yang, Jian] Westlake Lab Life Sci & Biomed, Hangzhou, Peoples R China.

[Liu, Shuli; Yang, Jian] Westlake Univ, Sch Life Sci, Hangzhou, Peoples R China.

[Guan, Dailu; Zhou, Huaijun; Cheng, Hao] Univ Calif Davis, Dept Anim Sci, Davis, CA 95616 USA.

通讯机构：

[Zhou, HJ ; Palmer, AA ; Li, JJ ] U

[Zhang, Z ] S

[Liu, GE ; Fang, LZ ] A

[Frantz, L ] L

Aarhus Univ, Ctr Quantitat Genet & Genom, Aarhus, Denmark.

语种：

英文

期刊：

Nature Genetics

ISSN：

1061-4036

年：

2025

卷：

期：

页码：

786-796

DOI：

10.1038/s41588-025-02121-5

基金类别：

Agriculture and Food Research Initiative Competitive grant from the USDA National Institute of Food and Agriculture [2022-67015-36215]; CellFood Hub (Aarhus University Foundation); Innovative Health Initiative Joint Undertaking [101165643]; China Agriculture Research System [CARS-35]

机构署名：

本校为其他机构

院系归属：

动物科学技术学院

摘要：

Genetic mutation and drift, coupled with natural and human-mediated selection and migration, have produced a wide variety of genotypes and phenotypes in farmed animals. We here introduce the Farm Animal Genotype–Tissue Expression (FarmGTEx) Project, which aims to elucidate the genetic determinants of gene expression across 16 terrestrial and aquatic domestic species under diverse biological and environmental contexts. For each species, we aim to collect multiomics data, particularly genomics and transcriptomics, from 50 tissues of 1,000 health...

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