National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21775132, 41571234]; Scientific Research Foundation of Hunan Provincial Education DepartmentHunan Provincial Education Department [16A204]; National Natural Science Foundation of Hunan provinceNatural Science Foundation of Hunan Province [2018JJ2388]; project of innovation team of the ministry of education [IRT_17R90]
机构署名：
本校为第一且通讯机构
院系归属：
资源环境学院
理学院
摘要：
A reliable and sensitive cancer cells DNA-templated silver nanoclusters probe has been proposed for screening DNA-targeted anticancer drugs in vitro. In this paper, the DNA-templated silver nanoclusters was used to investigate the binding between anthracycline antibiotics and DNA. The template of DNA-templated silver nanoclusters was extracted from human liver carcinoma cells directly, which can express the drug activities against cancer cells more direct than the normal cells DNA. The anti-tumor activities of the four drugs were validated by M...
