Abnormal small-world brain functional networks in obsessive-compulsive disorder patients with poor insight

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Lei, Hui;Cui, Yan;Fan, Jie;Zhang, Xiaocui;Zhong, Mingtian;...

通讯作者：

Zhu, Xiongzhao;Yao, Dezhong

作者机构：

[Fan, Jie; Zhang, Xiaocui; Zhu, Xiongzhao; Yi, Jinyao; Lei, Hui] Cent S Univ, Xiangya Hosp 2, Med Psychol Ctr, 139 Renmin Rd, Changsha 410011, Hunan, Peoples R China.

[Lei, Hui] Hunan Agr Univ, Coll Educ, Changsha, Hunan, Peoples R China.

[Fan, Jie; Zhang, Xiaocui; Zhu, Xiongzhao; Yi, Jinyao] Ctr South Univ, Med Psychol Inst, Changsha, Hunan, Peoples R China.

[Yao, Dezhong] Univ Elect Sci & Technol China, Ctr Informat BioMed, Key Lab NeuroInformat, Minist Educ, Chengdu, Sichuan, Peoples R China.

[Zhong, Mingtian] South China Normal Univ, Ctr Studies Psychol Applicat, Guangzhou, Guangdong, Peoples R China.

通讯机构：

[Zhu, Xiongzhao] C

[Yao, Dezhong] U

Cent S Univ, Xiangya Hosp 2, Med Psychol Ctr, 139 Renmin Rd, Changsha 410011, Hunan, Peoples R China.

Univ Elect Sci & Technol China, Ctr Informat BioMed, Key Lab NeuroInformat, Minist Educ, Chengdu, Sichuan, Peoples R China.

语种：

英文

关键词：

*Electroencephalograms;*Functional networks;*Graph theoretical analysis;*Obsessive-compulsive disorder;*Poor insight;*Small-world

期刊：

Journal of Affective Disorders

ISSN：

0165-0327

年：

2017

卷：

219

页码：

119-125

DOI：

10.1016/j.jad.2017.05.032

基金类别：

Role of funding source This work was supported by grants from the National Natural Science Foundation of China, China (grant number 31600893 to Hui Lei).

机构署名：

本校为其他机构

院系归属：

教育学院

摘要：

Background There are limited data on neurobiological correlates of poor insight in obsessive-compulsive disorder (OCD). This study explored whether specific changes occur in small-world network (SWN) properties in the brain functional network of OCD patients with poor insight. Method Resting-state electroencephalograms (EEGs) were recorded for 12 medication-free OCD patients with poor insight, 50 medication-free OCD patients with good insight, and 36 healthy controls. Results Both of the OCD groups exhibited topological alterations in the brain...

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Abnormal small-world brain functional networks in obsessive-compulsive disorder patients with poor insight

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