期刊论文

Huang, Mingzhi;Shi, Guorong

英文

Bioorganic & Medicinal Chemistry Letters

0960-894X

2019

29

11

1430-1433

10.1016/j.bmcl.2018.12.055

We would like to thank many colleagues at the National Engineering Research Center for Agrochemicals for their contributions to the discovery and the development of 4a and 11a . We also gratefully acknowledge the support for this work from the National Natural Science Foundation of China ( 21572050 , 21672057 ), the National Key Research & Development Pillar Program of China during the 13th Five-Year Plan Period (Grant No. 2016YFD0300708 ).

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A series of nitropyridyl-based dichloropropene ethers were prepared and evaluated for their insecticidal activities against main lepidopteran pests such as M. separate, P. xylostella and P. litura. The compounds showed a broad-spectrum of remarkable insecticidal activities. Especially 4a (2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-nitro-2-pyridyloxy]propyl ether) and 11a (2-(4-(3-(2,6-dichloro-4-((3,3-dichloroallyl)oxy)phenoxy)propoxy)phenoxy)-5-nitropyridine) displayed potent activities comparable to that of Pyridalyl, the only commercia...