Metabolite profiling, antioxidant and anti-aging activities of Siraitia grosvenorii pomace processed by solid-state fermentation with Eurotium cristatum
National Natural Science Foundation of China [32302611]; Key Research and Development Program of Hunan Province [2023NK2025]; Hunan Graduate Research Innovation Project [QL20210169]
机构署名：
本校为第一且通讯机构
院系归属：
食品科学技术学院
摘要：
Siraitia grosvenorii pomace (SGP) was processed by solid-state fermentation with Eurotium cristatum. Metabolite differences between non-fermented Siraitia grosvenorii pomace (NFSGP) and E. cristatum fermented Siraitia grosvenorii pomace (FSGP) were investigated by LC-MS/MS-based untargeted metabolomic analysis. The anti-oxidant and anti-aging effect of NFSGP and FSGP was investigated through in vitro and in vivo assays using Caenorhabditis elegans model. Results showed that 263 metabolites had significant changes after fermentation. Fermentation with E. cristatum significantly increase most po...
