It is known that about 99% microorganisms in natural environment couldn＇t be obtained their pure culture by traditional culture methods,but for extremophiles of extreme conditions is poorly understood.With the emergence of metagenomic technology,people could investigate the immense and unknown world of microorganisms in many ways.Investigators have studied many extreme habitats of the earth by this technology and acquired many novel accomplishments.The application of metagenomics for investigation of uncultured microorganisms in extr...
