期刊论文

Wang, G.

英文

遗传学报

1673-8527

2007

34

9

765-776

10.1016/S1673-8527(07)60087-3

This work was supported by grants from the Natural Science Foundation of China （No. 30470990, No. 30571063）, the ＂948＂ Project from the Minister of Agriculture in China, the ＂973＂ Project from the Minister of Science and Technology （No. 2006CB 101904）, Hunan Natural Science Foundation （No. 06JJ 10006） and Scientific Research Fund of Hunan Provincial Education department （No. 04A024）.Acknowledgement： We thank Miguel Vega-Sanchez and Troy Markham for their edit and valuable comments on this paper.

本校为第一且通讯机构

Plants employ multifaceted mechanisms to fight with numerous pathogens in nature. Resistance (R) genes are the most effective weapons against pathogen invasion since they can specifically recognize the corresponding pathogen effectors or associated protein(s) to activate plant immune responses at the site of infection. Up to date, over 70 R genes have been isolated from various plant species. Most R proteins contain conserved motifs such as nucleotide-binding site (NBS), leucine-rich repeat (LRR), Toll-interleukin-1 receptor domain (TIR, homologous to cytoplasmic domains of the Drosophila Toll...

植物与病原菌在长期的共进化和相互选择的过程中,逐渐形成了组织障碍、非寄主抗性和小种专化抗性等有效的防御机制。小种专化抗性（基因对基因抗性）主要是由植物抗病基因识别相应的病原菌无毒基因并激活植物体内抗病信号进而抵御病原菌的侵染。从目前已克隆的 70 多个抗病基因来看,它们在结构上具有高度保守性,主要包括核苷酸结合位点（NBS）,亮氨酸重复结构（LRR）, 蛋白激酶结构域（PK）, 果蝇蛋白 Toll 和哺乳动物蛋白质白细胞介素 1 受体[interleukin（IL）-1 receptor]类似结构域（TIR）, 双螺旋结构（CC）或亮氨酸拉链（LZ）和跨膜结构域（TM）等,其在抗病基因与病原菌无毒（效应）蛋白互...