Genome-wide identification of resistance genes and response mechanism analysis of key gene knockout strain to catechol in Saccharomyces cerevisiae

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成果类型：

期刊论文

作者：

Liao, Hong;Li, Qian;Chen, Yulei;Tang, Jiaye;Mou, Borui;...

通讯作者：

Yang, Yaojun;Wang, HY;Liu, BD

作者机构：

[Liao, Hong; Mou, Borui; Fu, Chun; Tang, Jiaye; Wang, Hanyu; Li, Jialian; Xiao, Ximeng; Chen, Yulei; Lu, Fujia; Long, Wencong; Feng, Peng; Li, Qian; Yang, Fengxuan; Xin, Wenli; Yang, Yaojun; Wang, HY; Yang, YJ] Leshan Normal Univ, Coll Life Sci, Bamboo Dis & Pests Control & Resources Dev Key Lab, Leshan, Sichuan, Peoples R China.

[Tang, Jiaye; Ma, Menggen; Chen, Yulei; Li, Qian] Sichuan Agr Univ, Coll Resources, Chengdu, Sichuan, Peoples R China.

[Li, Wei] Aba Prefecture Ecol Protect & Dev Res Inst, Wenchuan, Sichuan, Peoples R China.

[Han, Xuebing] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha, Hunan, Peoples R China.

[Liu, Beidong] Zhejiang A&F Univ, Sch Forestry & Biotechnol, State Key Lab Subtrop Silviculture, Hangzhou, Zhejiang, Peoples R China.

通讯机构：

[Wang, HY ; Yang, YJ] L

[Liu, BD ] Z

Leshan Normal Univ, Coll Life Sci, Bamboo Dis & Pests Control & Resources Dev Key Lab, Leshan, Sichuan, Peoples R China.

Zhejiang A&F Univ, Sch Forestry & Biotechnol, State Key Lab Subtrop Silviculture, Hangzhou, Zhejiang, Peoples R China.

Univ Gothenburg, Dept Chem & Mol Biol, Gothenburg, Sweden.

语种：

英文

关键词：

Saccharomyces cerevisiae;catechol;genome-wide identification;omics analysis;response mechanism

期刊：

Frontiers in Microbiology

ISSN：

1664-302X

年：

2024

卷：

页码：

1364425

DOI：

10.3389/fmicb.2024.1364425

基金类别：

National Natural Science Foundation of China [32200044]; Key Project of Science and Technology Bureau of LeShan Town [22ZDYJ0089]; Talent Research Startup Projects of Leshan Normal University [RC2022003]; Scientific Research and Cultivation Plan of Leshan Normal University [2022SSDJS010]; Leshan Normal University High-Level Talent Project [RC2021013]

机构署名：

本校为其他机构

院系归属：

生物科学技术学院

摘要：

Engineering Saccharomyces cerevisiae for biodegradation and transformation of industrial toxic substances such as catechol (CA) has received widespread attention, but the low tolerance of S. cerevisiae to CA has limited its development. The exploration and modification of genes or pathways related to CA tolerance in S. cerevisiae is an effective way to further improve the utilization efficiency of CA. This study identified 36 genes associated with CA tolerance in S. cerevisiae through genome-wide identification and bioinformatics analysis and t...

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Genome-wide identification of resistance genes and response mechanism analysis of key gene knockout strain to catechol in Saccharomyces cerevisiae

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