Genome-wide identification of the alkaloid synthesis gene family CYP450, gives new insights into alkaloid resource utilization in medicinal Dendrobium

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成果类型：

期刊论文

作者：

Li, Kang-Li;Liang, Yu-Min;Chen, Zhi;Zheng, Pei-Ji;Zhang, Guo-Qiang;...

通讯作者：

Chen, Bingjie;Xu, Q

作者机构：

[Liang, Yu-Min; Chen, Zhi; Zheng, Pei-Ji; Chen, Bingjie; Xu, Qing; Li, Kang-Li; Xu, Q] Guangzhou Med Univ, GMU GIBH Joint Sch Life Sci, Guangdong Hong Kong Macau Joint Lab Cell Fate Regu, Hong Kong 511436, Peoples R China.

[Zhang, Guo-Qiang] Fujian Agr & Forestry Univ, Key Lab Natl Forestry & Grassland Adm Orchid Conse, Fuzhou 350002, Peoples R China.

[Yan, Binghua] Hunan Agr Univ, Coll Resources & Environm, Changsha 410128, Hunan, Peoples R China.

[Rizwana, Humaira; Elshikh, Mohamed Soliman] King Saud Univ, Coll Sci, Dept Bot & Microbiol, PO 2455, Riyadh 11451, Saudi Arabia.

通讯机构：

[Chen, BJ; Xu, Q ] G

Guangzhou Med Univ, GMU GIBH Joint Sch Life Sci, Guangdong Hong Kong Macau Joint Lab Cell Fate Regu, Hong Kong 511436, Peoples R China.

语种：

英文

关键词：

Alkaloids;CYP450;Gene family;Genome-wide analysis;Medicinal Dendrobium

期刊：

International Journal of Biological Macromolecules

ISSN：

0141-8130

年：

2024

卷：

259

期：

Pt 2

页码：

129229

DOI：

10.1016/j.ijbiomac.2024.129229

基金类别：

National Natural Science Foundation of China [32300189]; Talent Project of Guangzhou Medical University High-level University Construction [B195002005025, 06- 410-2106132, 02-412-B205002-1005025]; King Saud University, Riyadh, Saudi Arabia [RSPD2023R1091]

机构署名：

本校为其他机构

院系归属：

资源环境学院

摘要：

The medicinal Dendrobium species of Orchidaceae possess significant pharmaceutical value, and modern pharmacological research has shown that Dendrobium contains many important active ingredients. Alkaloids, the crucial components of medicinal Dendrobium, demonstrate beneficial healing properties in cardiovascular, cataract, gastrointestinal, and respiratory diseases. Members of the cytochrome P450 monooxygenase (CYP) gene family play essential roles in alkaloid synthesis, participating in alkaloid terpene skeleton construction and subsequent modifications. Although studies of the CYP family ha...

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Genome-wide identification of the alkaloid synthesis gene family CYP450, gives new insights into alkaloid resource utilization in medicinal Dendrobium

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