Identification of a novel porcine Teschovirus 2 strain as causative agent of encephalomyelitis in suckling piglets with high mortality in China

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成果类型：

期刊论文

作者：

Liang, Wenqi;Wu, Xiangdong;Ding, Zhen;Zhong, Shengwei;Qian, Xinjie;...

通讯作者：

Ding, N.;Hu, R.

作者机构：

[Liu, Hao; Liang, Wenqi; Luo, Junrong; Cao, Huabin; Chen, Zheng; Ye, Pei; Ding, Zhen; Zhang, Jinhua; Zhong, Shengwei; Hu, Ruiming; Wu, Xiangdong; Qian, Xinjie; Hu, Guoliang] Jiangxi Agr Univ, Coll Anim Sci & Technol, Dept Vet Med, 1101 Zhimin Ave,Econ & Technol Dev Dist, Nanchang 330045, Jiangxi, Peoples R China.

[Liang, Wenqi; Luo, Junrong; Cao, Huabin; Hu, Ruiming; Hu, Guoliang] Jiangxi Agr Univ, Inst Anim Populat Hlth, Jiangxi Prov Key Lab Anim Hlth, 1101 Zhimin Ave,Econ & Technol Dev Dist, Nanchang 330045, Jiangxi, Peoples R China.

[Li, Zuohua] Hunan Agr Univ, Coll Vet Med, Changsha 410128, Peoples R China.

[Ding, Nengshui] Jiangxi Agr Univ, State Key Lab Pig Genet Improvement & Prod Technol, Nanchang 330045, Peoples R China.

[Ding, Nengshui] Aonong Grp, Key Lab Swine Nutr & Feed Sci Fujian Prov, Zhangzhou 363000, Peoples R China.

通讯机构：

[Nengshui Ding] S

[Ruiming Hu] D

State Key Laboratory for Pig Genetic Improvement and Production Technology, Jiangxi Agricultural University, Nanchang, China<&wdkj&>Key Laboratory of Swine Nutrition and Feed Science of Fujian Province, Aonong Group, Zhangzhou, China<&wdkj&>Department of Veterinary Medicine, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China

No. 1101 Zhimin Avenue, Economic and Technological Development District, Nanchang, China<&wdkj&>Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Economic and Technological Development District, Nanchang, China

语种：

英文

关键词：

Porcine teschovirus;Encephalitis;Phylogeny;Tertiary structure

期刊：

BMC Veterinary Research

ISSN：

1746-6148

年：

2023

卷：

期：

页码：

1-12

DOI：

10.1186/s12917-022-03549-1

基金类别：

This work was supported in part by the Science and Technology Program of the Education Department of Jiangxi Province (Grant Number: GJJ190192), the Natural Science Foundation of Jiangxi Province (Grant Number: 20202BAB205004), the Natural Science Foundation of Jiangxi Province (Grant Number: 2020ACBL215007), and the Program for Jiangxi Agriculture Research System (Grant Number: JXARS-01).

机构署名：

本校为其他机构

院系归属：

动物医学院

摘要：

Porcine Teschovirus (PTV), also named Teschovirus A, is prevalent in pig populations, mainly causing neurological symptoms, diarrhea, pneumonia, and reproductive failure, however the morbidity and mortality are usually low in pig farms. In this study, we reported a PTV outbreak investigation in one large-scale pig farm in China with severe symptoms including diarrhea, lethargy, locomotor ataxia, nystagmus, paralysis of the hind limbs, and coma in piglets. More importantly, the mortality reached 38% in suckling pigs, which is remarkably high in PTV history. A novel PTV strain, named HeNZ1, was ...

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Identification of a novel porcine Teschovirus 2 strain as causative agent of encephalomyelitis in suckling piglets with high mortality in China

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