Purified diet versus whole food diet and the inconsistent results in studies using animal models

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成果类型：

期刊论文

作者：

Zhang, Linyu;Li, Xin;Liu, Xiangyan;Wang, Xianglin;Li, Xiaowen;...

通讯作者：

Li, Rongfang;Wen, Lixin;Wang, J;Wen, LX

作者机构：

[Wang, Ji; Cheng, Xianyu; Li, Rongfang; Wen, Lixin; Li, RF; Li, Xin; Yan, Sisi; Zhu, Yuanyuan; Zhang, Linyu; Liu, Xiangyan; Li, Xiaowen; Wang, Xianglin; Wen, LX; Wang, J] Hunan Agr Univ, Coll Vet Med, Hunan Engn Res Ctr Livestock & Poultry Hlth Care, Changsha 410128, Peoples R China.

[Li, Rongfang; Wen, Lixin; Li, RF; Wen, LX] Hunan Collaborat Innovat Ctr Anim Prod Safety, Changsha 410128, Peoples R China.

[Wang, Ji; Wang, J] Changsha Lvye Biotechnol Co Ltd, Changsha 410100, Peoples R China.

通讯机构：

[Li, RF; Wen, LX; Wang, J ; Wen, LX ] H

Hunan Agr Univ, Coll Vet Med, Hunan Engn Res Ctr Livestock & Poultry Hlth Care, Changsha 410128, Peoples R China.

Hunan Collaborat Innovat Ctr Anim Prod Safety, Changsha 410128, Peoples R China.

Changsha Lvye Biotechnol Co Ltd, Changsha 410100, Peoples R China.

语种：

英文

期刊：

FOOD & FUNCTION

ISSN：

2042-6496

年：

2022

卷：

期：

页码：

4286-4301

DOI：

10.1039/d1fo04311k

基金类别：

We would like to thank the Special Funds for Construction of Innovative Provinces in Hunan Province (grant no. 2020NK2032) and the National Key R&D Program of China (grant no. 2016YDF0501200) for funding this research. We would also like to thankfully acknowledge Editage for English language editing.

机构署名：

本校为第一且通讯机构

院系归属：

动物医学院

摘要：

In animal models, purified diets (PDs) and whole food diets (WFDs) are used for different purposes. In similar studies, different dietary patterns may lead to inconsistent results. The aim of this study was to evaluate and compare the effects of WFDs and PDs on changes in the metabolism of mice. We found that different dietary patterns produced different results in lipid metabolism experiments. Compared with those of the PD-fed mice, the WFD-fed mice had higher body weights and serum glucose, serum lipid, and liver lipid levels (p < 0.01), as w...

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Purified diet versus whole food diet and the inconsistent results in studies using animal models

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