Anhedonia correlates with abnormal functional connectivity of the superior temporal gyrus and the caudate nucleus in patients with first-episode drug-naive major depressive disorder

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成果类型：

期刊论文

作者：

Yang, Xin-hua;Tian, Kai;Wang, Dong-fang;Wang, Yi;Cheung, Eric F. C.;...

通讯作者：

Chan, Raymond C. K.

作者机构：

[Tian, Kai; Yang, Xin-hua; Wang, Dong-fang] Hunan Agr Univ, Key Res Inst Philosophies & Social Sci Hunan Prov, Rural Children & Adolescents Res Ctr Hlth Promot, Inst Educ, Changsha, Hunan, Peoples R China.

[Wang, Yi; Yang, Xin-hua; Chan, Raymond C. K.] Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, Beijing, Peoples R China.

[Xie, Guang-rong] Cent S Univ, Key Lab Psychiat & Mental Hlth Hunan Prov, Natl Technol Inst Psychiat, Mental Hlth Inst,Xiangya Hosp 2, Changsha, Hunan, Peoples R China.

[Cheung, Eric F. C.] Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China.

[Chan, Raymond C. K.] Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China.

通讯机构：

[Chan, Raymond C. K.] C

Chinese Acad Sci, Inst Psychol, 16 Lincui Rd, Beijing 100101, Peoples R China.

语种：

英文

关键词：

*Anhedonia;*Caudate;*Functional connectivity;*Major depressive disorder

期刊：

Journal of Affective Disorders

ISSN：

0165-0327

年：

2017

卷：

218

页码：

284-290

DOI：

10.1016/j.jad.2017.04.053

基金类别：

"Strategic Priority Research Program (B)" of the Chinese Academy of Sciences [XDB02030002]; Beijing Training Project for the Leading Talents in S T [Z151100000315020]; Beijing Municipal Science & Technology Commission GrantBeijing Municipal Science & Technology Commission [Z161100000216138]; National Science Fund China [81571317]; Key Laboratory of Mental Health; CAS/SAFEA International Partnership Programme for Creative Research TeamsChinese Academy of Sciences [Y2CX131003]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2015M571149]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2016JJ3068]; Youth Project of Hunan Provincial Education Department [16B132]; Scientific Research Foundation of Hunan Agricultural University [15RCPT04]

机构署名：

本校为第一机构

院系归属：

教育学院

摘要：

Background Recent empirical findings have suggested that imbalanced neural networks may underlie the pathophysiology of major depressive disorder (MDD). However, the contribution of the superior temporal gyrus (STG) and the caudate nucleus to its pathophysiology remains unclear. Methods Functional magnetic resonance imaging (MRI) date were acquired from 40 patients with first-episode drug-naive MDD and 36 matched healthy controls during wakeful rest. We used whole-brain voxel-wise statistical maps to quantify within-group resting state function...

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Anhedonia correlates with abnormal functional connectivity of the superior temporal gyrus and the caudate nucleus in patients with first-episode drug-naive major depressive disorder

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