期刊论文

Effect of Bound Polyphenols in Psidium Guajava on Mice Intestinal Flora Structure and Diversity

中文

核农学报

1000-8551

2021

35

11

2589-2597

10.11869/j.issn.100-8551.2021.11.2589

国家自然科学基金项目（31671858）； 湖南省自然科学基金项目（2019JJ40114）； 湖南省教育厅重点项目（18A108）； 长沙市重点研发计划项目（kq1801016、kq1907039）；

本校为第一机构

为探究番石榴结合态多酚对小鼠肠道菌群的影响,本试验将CD-1小鼠分为空白组、高浓度组(500 mg·kg~(-1))和低浓度组(100 mg·kg~(-1))3组,在灌胃5周后,收集小鼠的无菌粪便,扩增肠道菌群16S rRNA基因高变域V3-V4,通过16S rRNA基因扩增子测序技术检测小鼠肠道菌群的α多样性、β多样性,以及门、属水平的物种组成。结果表明,与空白组相比,低浓度组中菌群的均匀性和丰富度显著提高(P

In order to explore the effects of bound polyphenols in Psidium guajava on fut microbiota in mice, CD-1 mice were divided into three groups, the blank group, the high concentration group (500 mg·kg~(-1)) and the low concentration group (100 mg·kg~(-1)). At the end of the fifth week of gavage, the gene hypervariable V3-V4 of 16S rRNA in the gut microbiota was amplified after sterile feces collection. The alpha and beta-diversity, the species composition of the gut microbiota at the phylum and genus levels were detected by 16S rRNA gene amplico...