期刊论文

Xiao, Hong-Bo

英文

Journal of Physiology and Biochemistry

1138-7548

2013

69

4

719-725

10.1007/s13105-013-0248-5

Hunan Provincial Science and Technology Department [2011NK2011, 2012NK4048]; Hunan Provincial Natural Science Foundation of ChinaNatural Science Foundation of Hunan Province [10JJ2028]

本校为第一且通讯机构

Angiopoietin-like protein 3 (Angptl3)-lipoprotein lipase (LPL) pathway may be a useful pharmacologic target for hyperlipidemia. The present study was conducted to test the effect of soluble fiber extracted from Undaria pinnatifida (UP), on hyperlipidemia in apolipoprotein E-deficient (ApoE(-/-)) mice. Forty mice were divided into four groups (n = 10): control group (C57BL/6J mice), ApoE(-/-) mice group, and two groups of ApoE(-/-) mice treated with UP fiber (5 or 10 % per day). UP soluble fiber treatment significantly decreased plasma and hepatic total cholesterol, triglycerides levels, plasma...