Macleaya cordata (willd.) R.Br. is a perennial herb of Papaveraceae. Macleaya cordata is rich in alkaloid resources, and its main functional active components are Sanguine, Chelerythine, Proto?pine, Allocryptopine and other isoquinoline alkaloids. It has many biological activities, such as anti-microbial, anti-inflammatory, anti-oxidation, insecticidal, anti-virus, anti-tumor and so on. In this pa?per, we reviewed the main biological activities of these isoquinoline alkaloids and the application of al?kaloids extracted from Macleaya cordata in the animal production. In order to provide a refer...